효소측정의 임상적 응용
- 최초 등록일
- 1999.02.19
- 최종 저작일
- 1999.02
- 5페이지/
한컴오피스
- 가격 무료
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본문내용
Mechanism for abnormal serum enzyme level
Increased level
Increased release
Necrosis : Myocardial infarction(AST, LD, CK, HBDH)
Acute Hepatitis(AST, ALT, OCT LD, LAP)
Acute pancreatitis(Amylase, Lipase)
Increased permeability without necrosis
: Progressive muscular dystrophy(CK, ALS, LD)
Increased tissue source of enzyme
: Neoplastic disease (carcinoma, lymphoma, leukemia)(LD, ALS)
Megaloblastic anemia(LD, ALS)
Osteoblastic lesion(Paget's disease, osteogenic sarcoma, rickets,
healing fracture)(ALP)
Impaired excretion of enzyme
: Uremia (Pepsinogen, Amylase)
Obstructive jaundice( ALP, LAP, r-GT, 5'-N)
Decreased level
Decreased formation
Genetic : Hypophosphatasia(ALP)
Wilson's disease(Ceruloplasmin)
Acholinesterasemia(Pseudocholinesterase)
Acquired : Hepatitis(Pseudocholinesterase)
Starvation(Amylase)
Enzyme ingibition
: Insecticide poisoning(Pseudocholinesterase)
Lack of cofactors
: Pregnancy(AST)
Cirrhosis
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