Introduction
As genetic engineers have developed “genetic modification technology”, new genetically modified(GM) crops have been out into the world. The major GM crops include soybean, corn, cotton and rapeseed. Soybean accounts for 50% of the area of cultivation of GM crops (ISAAA, 2017). However, soybean is one of the ingredients that causes an allergic reaction. Soybean has been known to have diverse allergens such as Gly m 5, Gly m 6, Gly m 7, Gly m Bd 30K, oleosin, and so on. Thus, whether genetic modification of beans changes the level of endogenous allergen is an important issue for patients who have allergies to soybeans as well as other ingredients (Matsuo et al., 2020).
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