방사선 유도 돌연변이체, 블랙베리 발효음료의알코올 대사 및 숙취 억제 효과 (Effect of Fermented Blackberry Drinks Formed from Radiation-induced Mutant on Alcohol Metabolism and Hangover in Rats)

서지정보

· 발행기관 : (사)한국방사선산업학회
· 수록지 정보 : 방사선산업학회지 / 7권 / 1호 / 75 ~ 80페이지
· 저자명 : 조병옥, 소양강, 이창욱, 조정근, 우현심, 진창현, 정일윤

초록

This study was designed to elucidate the effect of fermented blackberry drinks (BD) onalcohol metabolism and hangover in alcohol-treated rats. We showed that the administration ofBD increased the activity of alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) inalcohol-treated rats. Moreover, the administration of BD reduced the serum alcohol and acetaldehydeconcentrations in alcohol-treated rats. Furthermore, the administration of BD attenuatedthe levels of serum aspartate aminotransferase and alanine aminotransferase in alcohol-treatedrats. Taken together, these results suggest that BD plays an important role in alcohol metabolismand liver function by reducing blood alcohol and acetaldehyde through the activation of ADH andALDH in alcohol-treated rats and could be used as a functional anti-hangover drinks.

영어초록

This study was designed to elucidate the effect of fermented blackberry drinks (BD) onalcohol metabolism and hangover in alcohol-treated rats. We showed that the administration ofBD increased the activity of alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) inalcohol-treated rats. Moreover, the administration of BD reduced the serum alcohol and acetaldehydeconcentrations in alcohol-treated rats. Furthermore, the administration of BD attenuatedthe levels of serum aspartate aminotransferase and alanine aminotransferase in alcohol-treatedrats. Taken together, these results suggest that BD plays an important role in alcohol metabolismand liver function by reducing blood alcohol and acetaldehyde through the activation of ADH andALDH in alcohol-treated rats and could be used as a functional anti-hangover drinks.

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