[유기화학실험 A+] Diels-Alder Reaction (1,3-Butadiene) (prelab/프리랩/예비보고서)

소개

"[유기화학실험 A+] Diels-Alder Reaction (1,3-Butadiene) (prelab/프리랩/예비보고서)"에 대한 내용입니다.

목차

1. Objectives
2. Principles & Methods
3. References

본문내용

Objectives: Diels-Alder reaction of (E,E)-2,4-hexadien-1-ol and maleic anhydride can be carried out to synthesize (3aR,4S,5S,7aR)-5-methyl-3-oxo-1,3,3a,4,5,7a-hexahydroisobenzofuran-4-carboxylic acid.

Principles & Methods
(1) Principles: Diels-Alder Reaction is a cycloaddition between a 1,3-diene and an electron-poor alkene (= dienophile) to provide in a single step a cyclohexene derivative.

참고자료

· John A. Landgrebe. “Theory and Practice in the Organic Laboratory” 5th ed. 2005. Thomson Wadsworth.
· Leory G. and Jan William Simek. “Organic Chemistry” 2017 Pearson.
· McDaniel, K. F., & Weekly, R. M. (1997). The Diels-Alder Reaction of 2,4-Hexadien-1-ol with Maleic Anhydride: A Novel Preparation for the Undergraduate Organic Chemistry Laboratory Course. Journal of Chemical Education, 74(12), 1465. doi:10.1021/ed074p1465
· https://chem.libretexts.org/Bookshelves/Organic_Chemistry/Organic_Chemistry_Lab_Techniques_(Nichols)/02%3A_Chromatography/2.03%3A_Thin_Layer_Chromatography_(TLC)/2.3F%3A_Visualizing_TLC_Plates
· https://chem.libretexts.org/Bookshelves/Organic_Chemistry/Map%3A_Organic_Chemistry_(Wade)/16%3A_Conjugated_Systems_Orbital_Symmetry_and_Ultraviolet_Spectroscopy/16.06%3A_The_Diels-Alder_(4__2)_Cycloaddition_Reaction
· https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/lactonization
· Wikipedia (“Diels-Alder reaction”, “Lactone”, “Enantiomer”)
· https://pubchem.ncbi.nlm.nih.gov
· chemspider.com