Thyroid emergency
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Thyroid emergency
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2024.04.13
문서 내 토픽
  • 1. Primary hypothyroidism
    Hashimoto 갑상선염, 수술적 제거 또는 방사능 소각으로 인한 갑상선 기능 손상, 특정 약물(lithium, α-interferon, interleukin, tyrosine kinase inhibitors, amiodarone) 등이 갑상선 기능을 저하시켜 갑상선 기능 저하 증상을 유발할 수 있다.
  • 2. Secondary hypothyroidism
    뇌하수체에서 TSH 분비 부족 또는 갑상선 자극 호르몬 방출을 조절하는 호르몬 부족으로 인해 갑상선 호르몬 분비가 충분하지 않아 갑상선 기능 저하 증상이 나타날 수 있다.
  • 3. Euthyroid
    중환자 또는 심각한 전신 질환을 가진 환자에서 T3 또는 T4 수준이 낮지만 임상적으로 갑상선 기능이 정상인 상태를 의미한다. 이는 병리적인 상태가 아닌 질환으로 인한 일시적인 갑상선 기능 변화를 나타낸다.
  • 4. Diagnosis
    갑상선 기능 저하 진단은 주로 혈액 검사를 통해 TSH, T4, T3 수준을 확인하며, myxedema crisis 진단은 주로 임상 증상과 신체 검사에 의존한다. 치료 전 기준 수준 확인을 위해 추가적인 검사(전해질, 혈당, 심전도, 영상 검사 등)가 필요할 수 있다.
  • 5. Treatment
    갑상선 기능 저하 환자에게 경구 레보티록신을 투여하며, 50세 이상이거나 심장 질환이 있는 경우 초기 용량을 더 낮게 시작한다. 환자 상태가 위급한 경우 호흡, 순환 관리, 정맥주사 요법, 혈관 수축제, 저체온증 치료, 스테로이드 투여 등의 지원적 치료가 필요할 수 있다.
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  • 1. Primary hypothyroidism
    Primary hypothyroidism is a condition where the thyroid gland fails to produce enough thyroid hormones, leading to a wide range of symptoms such as fatigue, weight gain, cold intolerance, and cognitive impairment. This is often caused by autoimmune disorders like Hashimoto's thyroiditis, where the body's immune system attacks and damages the thyroid gland. Proper diagnosis and management of primary hypothyroidism are crucial, as untreated hypothyroidism can lead to more serious health complications. Treatment typically involves daily oral administration of synthetic thyroid hormones, such as levothyroxine, to restore normal thyroid function and alleviate symptoms. Regular monitoring and dose adjustments are necessary to ensure optimal thyroid hormone levels and overall well-being for individuals with primary hypothyroidism.
  • 2. Secondary hypothyroidism
    Secondary hypothyroidism is a less common form of hypothyroidism, where the underlying cause is a problem with the pituitary gland or the hypothalamus, rather than the thyroid gland itself. In this condition, the pituitary gland fails to produce enough thyroid-stimulating hormone (TSH), which is necessary for the thyroid gland to function properly and produce adequate amounts of thyroid hormones. Causes of secondary hypothyroidism can include pituitary tumors, pituitary gland damage, or certain medications. Diagnosis of secondary hypothyroidism often involves measuring both TSH and free thyroid hormone levels, as the typical elevated TSH seen in primary hypothyroidism may not be present. Treatment typically involves replacing the missing thyroid hormones, as well as addressing the underlying cause of the pituitary or hypothalamic dysfunction. Careful monitoring and management are essential to ensure proper thyroid function and overall health in individuals with secondary hypothyroidism.
  • 3. Euthyroid
    Euthyroid refers to a normal, healthy thyroid function, where the thyroid gland is producing the appropriate amount of thyroid hormones (T4 and T3) to meet the body's metabolic needs. In a euthyroid state, the levels of thyroid hormones and thyroid-stimulating hormone (TSH) are within the normal reference ranges, indicating that the thyroid gland is functioning properly. Individuals with a euthyroid status typically do not experience any symptoms related to thyroid dysfunction, such as fatigue, weight changes, or mood disturbances. Maintaining a euthyroid state is essential for overall health and well-being, as thyroid hormones play a crucial role in regulating various physiological processes, including metabolism, growth, and development. Regular thyroid function tests can help healthcare providers monitor and ensure that an individual's thyroid status remains within the normal, euthyroid range.
  • 4. Diagnosis
    Accurate diagnosis of thyroid disorders, such as hypothyroidism and hyperthyroidism, is crucial for proper management and treatment. The diagnostic process typically involves a combination of medical history, physical examination, and laboratory tests. The initial step is often a blood test to measure the levels of thyroid hormones, including thyroid-stimulating hormone (TSH), free thyroxine (T4), and free triiodothyronine (T3). These tests can help differentiate between primary, secondary, and subclinical thyroid disorders. Additional tests, such as thyroid antibody tests, imaging studies (e.g., thyroid ultrasound), and in some cases, a thyroid biopsy, may be necessary to confirm the underlying cause and guide appropriate treatment. Prompt and accurate diagnosis is crucial, as untreated thyroid disorders can lead to significant health complications. Healthcare providers should work closely with patients to ensure a comprehensive and personalized approach to thyroid disease diagnosis and management.
  • 5. Treatment
    The treatment of thyroid disorders, such as hypothyroidism and hyperthyroidism, is essential for restoring normal thyroid function and improving overall health. The primary treatment approach for hypothyroidism, the most common thyroid disorder, is the administration of synthetic thyroid hormones, typically levothyroxine, to replace the deficient thyroid hormones. This medication is taken daily, and the dosage is carefully adjusted based on regular monitoring of thyroid hormone levels. For hyperthyroidism, treatment options may include antithyroid medications, radioactive iodine therapy, or in some cases, surgical removal of the thyroid gland. The specific treatment plan is tailored to the individual's condition, underlying cause, and overall health status. Effective management of thyroid disorders also involves addressing any underlying causes, such as autoimmune conditions or pituitary gland dysfunction. Regular follow-up appointments and close collaboration between patients and healthcare providers are essential to ensure optimal thyroid function, manage symptoms, and prevent long-term complications. Ongoing monitoring and adjustments to treatment are often necessary to maintain a euthyroid state and optimize overall health and well-being.
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