여드름의 병태생리와 치료

소개

Acne 결정판입니다

모 대학병원 피부과 레지던트 1년차의 여드름 병태생리 및 치료 정리한 PPT입니다

최신 논문 약 10여편 참고하였고 Fitz. 도 요약하였습니다.

목차

1. Recognizing the Chronicity of Acne

2. Pathogenesis of Acne3. Topical and Oral Treatment of Acne
A. The changing role of antibiotics in managing acne
B. Retinoid-based combination therapy for acne
C. The role of topical retinoids in acne maintenance therapy
D. The role of topical retinoids in acne maintenance therapy
E. Oral Retinoids

4. Optimizing adherence with acne therapy

본문내용

What is New in Acne Pathophysiology
1. Inflammation events have been found to precede hyperkeratinization
2. P. acne contributes to inflammation via activation of toll-like
receptor(TLR) on the membranes of inflammatory cells.
3. Peroxisome proliferator-activated receptors partly regulate sebum
production.
4. The sebaceous gland is a neuroendocrine-inflammatory organ that
likely coordinates and executes a local response to stress and
normal functions.

참고자료

· JAAD 2009 May;60(5 Suppl):S1-50
· JAAD 2003 Jul;49(1 Suppl):S1-37
· JAAD 2003 Sep;49(3 Suppl):S200-10
· Br J Dermatol 2010 Nov;29
· JEADV 2011 Mar; 24 Epub ahead of print
· British J Dermatol 2005;153:1105-1113
· J immunol 2002 ;169;1535-1541
· Am J Pathol 2005, 166:1691-1699
· 대피지2009;47(3):287-294
· 각종 대피지 논문