Growth factor control of dental stem cells in regenerative dentistry

소개

성장인자로 치음의 줄기세포를 컨트롤하여 이의 세포를 재생시키는 연구논문들을 리뷰 한것입니다. (어려운 한국말이 서툴러서 설명이 좀 이상합니다...;;)

목차

Introduction

Mesenchymal Stem Cells
- Dental pulp associated stem cells
- Periodontium associated stem cells

Growth Factors involved in Periodontal Regeneration
- IGF-I and PDGF
- Bone morphogenetic proteins (BMPs)
- Fibroblast growth factor (FGF)
- Brain-derived neurotrophic factor (BDNF)

Conclusion

References (6 장)

Figures (2 장)

본문내용

Introduction
The periodontium is the tooth supporting tissues composed of two hard (cementum and alveolar bone) and two soft (periodontal ligament and gingival) tissues. The periodontium can be inherited or acquired, and the most significant among these is periodontitis. Periodontitis is a chronic inflammatory disease caused by the bacterial biofilm that forms around teeth and progressively destroys the periodontium, ultimately resulting in the loss of the affected teeth. Peridontitis occurs to some degree in all cultures and may threaten quality of life as oral functions are concerned. Conventional periodontal treatment can mechanically remove bacterial biofilm to restrict the gingival inflammatory process and the progression of periodontitis but cannot fully restore normal structure and function because periodontium has a limited capacity for natural regeneration; once the disease becomes established, spontaneous regeneration does not occur without some form of therapeutic treatment. Periodontal regeneration involves complex series of events that requires stimulation of stem cells to differentiate into specialized cells, such as cementoblasts, osteoblasts and fibroblasts,

참고자료

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