대사증후군 집단의 심박동수 변이의 특징 (Characteristics of Heart Rate Variability among Adults with Metabolic Syndrome)

서지정보

· 발행기관 : 대한생물정신의학회
· 수록지 정보 : 생물정신의학 / 15권 / 3호 / 186 ~ 193페이지
· 저자명 : 여도환, 김정일, 강동묵, 김정연, 조정진, 김원, 임성견, 우종민

초록

Objectives: The authors tried to investigate the characteristics of Heart Rate Variability(HRV) among the subjects with metabolic syndrome for testing the possibility of clinical application of HRV in evaluating metabolic syndrome.

Methods: We examined the difference of the means of HRV between 122 subjects of metabolic syndrome and 1057 healthy controls using T-test, and the change of means in HRV according to increasing risk factors of metabolic syndrome. Using multiple regression analysis, we examined the association of HRV with the risk factors of metabolic syndrome.

Results: The HRV indices including SDNN (Standard Deviation of all normal NN intervals), RMSSD (the square Root of the Mean Squared Differences of successive all normal NN interval), TP (Total Power), LF (Low Frequency), and HF (High Frequency) was significantly lower in metabolic syndrome group than in normal control group, and the means of all HRV indices except LF/HF were decreased consistently according to increasing risk factors of metabolic syndrome. The fasting glucose, triglyceride, and waist circumference were dependent factors that contributed significantly to the change of HRV.

Conclusions: These findings suggest metabolic syndrome adversely affects cardiac autonomic system and HRV could be useful method for evaluating metabolic syndrome.

영어초록

Objectives: The authors tried to investigate the characteristics of Heart Rate Variability(HRV) among the subjects with metabolic syndrome for testing the possibility of clinical application of HRV in evaluating metabolic syndrome.

Methods: We examined the difference of the means of HRV between 122 subjects of metabolic syndrome and 1057 healthy controls using T-test, and the change of means in HRV according to increasing risk factors of metabolic syndrome. Using multiple regression analysis, we examined the association of HRV with the risk factors of metabolic syndrome.

Results: The HRV indices including SDNN (Standard Deviation of all normal NN intervals), RMSSD (the square Root of the Mean Squared Differences of successive all normal NN interval), TP (Total Power), LF (Low Frequency), and HF (High Frequency) was significantly lower in metabolic syndrome group than in normal control group, and the means of all HRV indices except LF/HF were decreased consistently according to increasing risk factors of metabolic syndrome. The fasting glucose, triglyceride, and waist circumference were dependent factors that contributed significantly to the change of HRV.

Conclusions: These findings suggest metabolic syndrome adversely affects cardiac autonomic system and HRV could be useful method for evaluating metabolic syndrome.

참고자료

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