산벚나무(Prunus sargentii R.) 수피의 화장품활성에 관한 연구 (A Study on the Cosmeceutical activities of Prunus Sargentii R.)

서지정보

· 발행기관 : 한국응용생명화학회
· 수록지 정보 : Applied Biological Chemistry / 51권 / 1호 / 70 ~ 78페이지
· 저자명 : 박정미, 이진영, 박태순, 현석준, 김한혁, 조영제, 권오준, 손애량, 김동석, 안봉전

초록

Prunus sargentii R. of Rosaceae familiy, has been reported to have radical scavenging activity and
anti-inflammatory effect. On these facts, biological activity and safety test were conducted to evaluate
biological activities of the extracts of P. sargentii R. as a potential pharmaceutical ingredient.
The electron donating ability of its ethanol extracts at a 500 ppm level showed 92%, which was
higher than that of hot water extract (59%), the superoxide dismutase (SOD)-like activity of the
water extract of P. sargentii R. was about 50%, the ethanol extract of P. sargentii R. was about
40% at 1,000 ppm concentration. Xanthine oxidase inhibition by the water extract of P. sargentii
R. was about 40% and that by the ethanol extract was 60% respectively at 500 ppm concentration.
From the measurement on lipid oxidation, the Cu2+ chelating effect of the ethanol extract was
higher than that of hot water extract. The Fe2+chelating effect was also shown to be about 80% at
a 500 ppm concentration in both hot water extract and ethanol extract. The tyrosinase inhibition
effect related to skin-whitening was 26% by hot water extract and 20% by ethanol extract respectively
at a 1,000 ppm. Hyaluronidase inhibition activity related to the anti-inflammation effect was
96% in ethanolic extract at a 500 ppm. Clear zones formed by P. sargentii R. against the human
skin-resident micro-flora such as Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli
and Propionibacterium acnes indicated that antimicrobial activity of the ethanol extract was higher
than that of the hot water extract.

영어초록

Prunus sargentii R. of Rosaceae familiy, has been reported to have radical scavenging activity and
anti-inflammatory effect. On these facts, biological activity and safety test were conducted to evaluate
biological activities of the extracts of P. sargentii R. as a potential pharmaceutical ingredient.
The electron donating ability of its ethanol extracts at a 500 ppm level showed 92%, which was
higher than that of hot water extract (59%), the superoxide dismutase (SOD)-like activity of the
water extract of P. sargentii R. was about 50%, the ethanol extract of P. sargentii R. was about
40% at 1,000 ppm concentration. Xanthine oxidase inhibition by the water extract of P. sargentii
R. was about 40% and that by the ethanol extract was 60% respectively at 500 ppm concentration.
From the measurement on lipid oxidation, the Cu2+ chelating effect of the ethanol extract was
higher than that of hot water extract. The Fe2+chelating effect was also shown to be about 80% at
a 500 ppm concentration in both hot water extract and ethanol extract. The tyrosinase inhibition
effect related to skin-whitening was 26% by hot water extract and 20% by ethanol extract respectively
at a 1,000 ppm. Hyaluronidase inhibition activity related to the anti-inflammation effect was
96% in ethanolic extract at a 500 ppm. Clear zones formed by P. sargentii R. against the human
skin-resident micro-flora such as Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli
and Propionibacterium acnes indicated that antimicrobial activity of the ethanol extract was higher
than that of the hot water extract.

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