추출조건에 따른 익모초 물추출물의 생리활성 비교 (Physiological properties of Leonurus sibiricus water extracts with different extraction condition)

서지정보

· 발행기관 : 한국식품저장유통학회
· 수록지 정보 : Food Science and Preservation / 20권 / 4호 / 592 ~ 596페이지
· 저자명 : 서지형, 정용진

초록

익모초 가공을 위한 기본 추출조건을 확립하기 위하여 3가지 조건으로 익모초 물추출물(열수추출물(Ⅰ), 고온고압-열수추출물(Ⅱ), 습식분쇄-열수추출물(Ⅲ))을 제조하고 이들의 생리적 특성을 비교하였다. 각 추출조건에 대한 수율은 13.02～15.90%로 유의적인 차이가 없었고, 총 폴리페놀 함량은 추출물(Ⅱ)와 (Ⅲ)에서 유의적으로 높았다. 전자공여능에 대한 IC50은 추출물(Ⅱ)에서 가장 낮았고 그 뒤로 추출물(Ⅲ) < 추출물(Ⅰ)순으로 유의적인 차이를 나타내었으며, ABTS라디칼 소거활성은 추출물(Ⅱ)와 (Ⅲ)에서 유의적으로 높았다. 아질산염 소거능은 추출조건간 유의적인 차이가 없었으며, ACE저해 활성은 고농도(5mg/mL)의 추출물에 대해 추출물(Ⅰ)보다 추출물(Ⅱ)와 (Ⅲ)에서 유의적으로 높았다.

영어초록

To stabilize the basal extraction conditions of Leonuri herbal products, three kinds of Leonurus sibiricus water extracts were prepared with different extraction conditions (boiling extraction (I), high thermal process & boiling extraction (II), and wet grinding & boiling extraction (III)), and their physiological properties were investigated. The extraction yields of the L. sibiricus water extracts were from 13.02 to 15.90%, with no significant difference among them. The polyphenol contents were significantly high in extracts (II) and (III) than in extract (I). The IC50 for the electron-donating ability was the smallest in extracts (II), (III) and (I) in ascending order. The ABTS radical scavenging ability was significantly higher in extracts (II) and (III) than in extract (I). Also, the ACE in hibition ability for 5 mg/mL of each extract was high in extracts (II) and (III), but there was no significant difference among the three extracts in terms of their nitrite scavenging abilities. Extraction processes (II) and (III) were shown to be useful for preparing Leonurus sibiricus water extracts with healthful properties.

참고자료

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