꼬시래기 유래 아가로즈와 블루베리 열매 추출물을 이용한 화장용 에멀젼 개발 (Development of Cosmetic Emulsion Using Blueberry Fruit Extract and Agarose from Gracilaria verrucosa)

서지정보

· 발행기관 : 한국생물공학회
· 수록지 정보 : KSBB Journal / 31권 / 4호 / 256 ~ 262페이지
· 저자명 : 최문희, 김용운, 김미숙, 신현재

초록

The need for natural cosmetic ingredients has been increasing over the world nowadays. Agarose, a natural polymerfrom red seaweeds, has high hydrophilic character and a function of scaffolder. As skin moisturizer, agarose is adequate for percutaneous absorption. While, blueberry fruits extract possesses rich procyanidins and anthocyanins which show health benefits, anti-oxidant effect, anti-aging and anti-melanogenesis. Stability, sensory preference, skin trouble of the emulsion formula are important for cosmetic product development. In this study, we manufactured an emulsion formula for skin moisturizers using the two ingredients and tested emulsion stability and skin trouble. Total phenolic contents of the blueberry fruits extract were evaluated as well as tyrosinase inhibitory and collagenase inhibitory activities. IC50 values of blueberry fruits extract for anti-tyrosinase and anti-collagenase activities were 168 and 112 μg/mL, respectively using gallic acid as a control (64.8 μg/mL). The stability (pH and viscosity) of the formula containing 2% blueberry fruits extracts and 0.1% agarose was measured at five different temperatures (room temp., 25oC, 55oC, 45oC, 55oC) under the sun light at 2 day intervals for 12 days. There has been little pH change at the different temperatures. According to the sensory evaluation, there was no significant flavor, discoloration and physical changes of the formula at 25-65oC. These results suggest that emulsion formula containing blueberry extract andagarose could be used as a candidate for lotion and essence products.

영어초록

The need for natural cosmetic ingredients has been increasing over the world nowadays. Agarose, a natural polymerfrom red seaweeds, has high hydrophilic character and a function of scaffolder. As skin moisturizer, agarose is adequate for percutaneous absorption. While, blueberry fruits extract possesses rich procyanidins and anthocyanins which show health benefits, anti-oxidant effect, anti-aging and anti-melanogenesis. Stability, sensory preference, skin trouble of the emulsion formula are important for cosmetic product development. In this study, we manufactured an emulsion formula for skin moisturizers using the two ingredients and tested emulsion stability and skin trouble. Total phenolic contents of the blueberry fruits extract were evaluated as well as tyrosinase inhibitory and collagenase inhibitory activities. IC50 values of blueberry fruits extract for anti-tyrosinase and anti-collagenase activities were 168 and 112 μg/mL, respectively using gallic acid as a control (64.8 μg/mL). The stability (pH and viscosity) of the formula containing 2% blueberry fruits extracts and 0.1% agarose was measured at five different temperatures (room temp., 25oC, 55oC, 45oC, 55oC) under the sun light at 2 day intervals for 12 days. There has been little pH change at the different temperatures. According to the sensory evaluation, there was no significant flavor, discoloration and physical changes of the formula at 25-65oC. These results suggest that emulsion formula containing blueberry extract andagarose could be used as a candidate for lotion and essence products.

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