Meta-analysis of the Prevalence of Canine Heartworm Infection in Korea

서지정보

· 발행기관 : 한국임상수의학회
· 수록지 정보 : 한국임상수의학회지 / 26권 / 4호 / 311 ~ 316페이지
· 저자명 : 박선일

초록

The purpose of this meta-analysis was to collect data from the literatures reporting prevalence of canine
heartworm (HW) infection in an effort to emphasize the preventive importance of the disease and to serve as baseline
data for further studies related to the disease management. Fourteen studies regarding the prevalence of HW infection
published during the 1996-2007 were identified using the meta-analytic approach, involving a total of 1,790 cases
by microfilarial test and 3,277 cases by enzyme-linked immunosorbent assay (ELISA) antigen test for adult worms.
Data analysis was performed separately for pet and military dogs. The overall apparent prevalence of HW infection
in pet dogs by microfilarial test and ELISA was 11.7% (183/1,563) and 16.5% (379/2,302), respectively (p < 0.001). No
significant difference in prevalence by microfilaria and ELISA was observed between sexes whether assessed by data
separately or pooled together. Compared to before 2000, the prevalence by microfilaria after 2000 has increased from
2.5% to 13.1% (p < 0.001), and the rate of adult worm has also increased from 9.9% to 20.3% (p < 0.001). The
prevalence determined by ELISA was found to increase with age: 20.7% (n = 1,003) of dogs older than 2 years were
positive, compared with 5.0% of dogs (n = 701) under 2 years of age (p < 0.001). Also, outdoor dogs showed significantly
higher prevalence than indoor dogs (37.9% versus 3.4%; p < 0.001). For military dogs, the overall prevalence was
38.3% (87/227; 95% CI, 32.1 − 44.7%) by microfilarial test and 38.5% (375/975; 95% CI, 35.4 − 41.6%) by ELISA. This
rate was significantly higher than that of pet dogs (p < 0.001). Occult infection rate of 37.5% and 66.7% was found
in pet and military dogs, respectively.

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