병동 내 주 사용 항암제 약물 정리

문서 내 토픽

1. Taxol Inj.

Taxol Inj.는 진행성 비소세포 폐암 치료의 1차 요법제이며, 3주마다 175mg/m^{2}를 3시간에 걸쳐 정주투여 후, 시스플라틴 80mg/m^{2}를 점적정주하는 방법으로 투여합니다. 투여 전 덱사메타손, 디펜히드라민, 시메티딘 등의 전처치가 필요하며, 투여 후 부작용 관찰이 필요합니다.
2. Cisplatin Inj.

Cisplatin Inj.는 Taxol Inj.와 병용하여 진행성 비소세포 폐암 치료의 1차 요법제로 사용됩니다. 70~90mg/m^{2}을 1일 1회 투여하며, 적어도 3주간 휴약(1주기)합니다. 투여 전 수액 주입 등의 전처치가 필요합니다.
3. Herceptin Inj.

Herceptin Inj.는 HER2 양성 전이성 유방암 환자 치료에 사용됩니다. 초기부하용량은 4mg/kg, 유지용량은 2mg/kg이며, 3주요법의 경우 초기부하용량은 8mg/kg, 유지용량은 6mg/kg입니다. 투여 전 전처치가 필요합니다.
4. Doxorubicin

Doxorubicin은 1일 1회 60~75mg/m^{2} IV로 투여하며, 3주간 휴약(1주기)합니다. 투여 전 전처치가 필요하며, 혈관통, 정맥염 유발 시 주사속도를 늦추어야 합니다.
5. 5-FU Inj.

5-FU Inj.는 전이성 결장/직장암 1차 치료제로 5-FU와 병용하여 사용되며, 소세포폐암 치료에도 사용됩니다. 1일 5~15mg을 5%DW 300~500mL mix하여 5일간 매일 점적 IV합니다. 방사선요법, 항종양제와 병용 투여할 수 있습니다.
6. Oxaliplatin Inj.

Oxaliplatin Inj.는 전이성 결장/직장암 1차 치료제로 5-FU와 병용하여 사용됩니다. 85mg/m^{2}를 매 2주마다 IV 투여합니다.
7. Xeloda Tab.

Xeloda Tab.은 진행성 위암의 1차 치료 및 수술 후 보조요법에 사용됩니다. 1일 2회(아침, 저녁) 1000mg/m^{2}을 2주간 경구 투여합니다.
8. Carboplatin Inj.

Carboplatin Inj.는 초기 1회 400mg/m^{2}을 IV 투여하며, 이후 4주 1회 단기간 IV 투여합니다. 시스플라틴과 병용하여 사용할 수 있습니다.
9. 항암제 투약 전 약물

항암제 투약 전 Emend Cap., Dexamethasone Inj., Gaster Inj., Peniramin Inj. 등의 약물을 코르티코스테로이드 및 5-HT3 길항제와 병용하여 3일간 투여합니다. 이는 항암화학요법에 의한 구역, 구토 예방을 위함입니다.
10. 기타 약물

D-manitol 20%는 약물중독 시의 배설 촉진, Atropine Inj.는 경련성 변비 및 위운동항진 치료, Ferbon Inj.는 진행성 대장암 치료 시 5-FU와 병용하여 사용됩니다.

Easy AI와 토픽 톺아보기

1. Taxol Inj.

Taxol (paclitaxel) is a widely used chemotherapy drug for the treatment of various types of cancer, including breast, ovarian, and lung cancer. It works by disrupting the normal function of microtubules, which are essential for cell division. Taxol is generally well-tolerated, but it can cause side effects such as neuropathy, hair loss, and hypersensitivity reactions. Careful monitoring and management of these side effects is important to ensure the safe and effective use of Taxol in cancer treatment.
2. Cisplatin Inj.

Cisplatin is a platinum-based chemotherapy drug that is commonly used to treat a variety of solid tumors, including lung, ovarian, testicular, and head and neck cancers. It works by forming DNA adducts, which interfere with DNA replication and transcription, leading to cell death. Cisplatin can be highly effective, but it is also associated with significant side effects, such as nephrotoxicity, ototoxicity, and neuropathy. Careful patient selection, dose optimization, and supportive care are essential to manage these side effects and ensure the safe and effective use of cisplatin in cancer treatment.
3. Herceptin Inj.

Herceptin (trastuzumab) is a targeted therapy used to treat HER2-positive breast cancer. It works by binding to the HER2 protein, which is overexpressed in these types of breast cancers, and inhibiting its signaling. Herceptin has been shown to significantly improve outcomes for patients with HER2-positive breast cancer, both in the early and metastatic settings. While generally well-tolerated, Herceptin can cause cardiac toxicity, and patients receiving this medication require close monitoring and management of this potential side effect.
4. Doxorubicin

Doxorubicin is an anthracycline chemotherapy drug that is widely used to treat a variety of cancers, including breast, lung, and hematological malignancies. It works by intercalating into DNA and inhibiting topoisomerase II, leading to DNA damage and cell death. Doxorubicin is a highly effective chemotherapy agent, but it is also associated with significant side effects, such as cardiotoxicity, myelosuppression, and mucositis. Careful patient selection, dose optimization, and supportive care are essential to manage these side effects and ensure the safe and effective use of doxorubicin in cancer treatment.
5. 5-FU Inj.

5-Fluorouracil (5-FU) is a pyrimidine analog chemotherapy drug that is commonly used to treat a variety of solid tumors, including colorectal, breast, and head and neck cancers. It works by inhibiting the enzyme thymidylate synthase, which is essential for DNA synthesis. 5-FU is generally well-tolerated, but it can cause side effects such as myelosuppression, mucositis, and hand-foot syndrome. Careful patient selection, dose optimization, and supportive care are important to manage these side effects and ensure the safe and effective use of 5-FU in cancer treatment.
6. Oxaliplatin Inj.

Oxaliplatin is a platinum-based chemotherapy drug that is commonly used to treat colorectal cancer, both in the adjuvant and metastatic settings. It works by forming DNA adducts, which interfere with DNA replication and transcription, leading to cell death. Oxaliplatin is generally well-tolerated, but it can cause significant side effects, such as peripheral neuropathy, myelosuppression, and gastrointestinal toxicity. Careful patient selection, dose optimization, and supportive care are essential to manage these side effects and ensure the safe and effective use of oxaliplatin in cancer treatment.
7. Xeloda Tab.

Xeloda (capecitabine) is an oral chemotherapy drug that is commonly used to treat colorectal and breast cancers. It is a prodrug that is converted to 5-fluorouracil (5-FU) in the body, which then inhibits DNA synthesis and cell division. Xeloda is generally well-tolerated, but it can cause side effects such as hand-foot syndrome, diarrhea, and myelosuppression. Careful patient selection, dose optimization, and supportive care are important to manage these side effects and ensure the safe and effective use of Xeloda in cancer treatment.
8. Carboplatin Inj.

Carboplatin is a platinum-based chemotherapy drug that is commonly used to treat a variety of solid tumors, including lung, ovarian, and head and neck cancers. It works by forming DNA adducts, which interfere with DNA replication and transcription, leading to cell death. Carboplatin is generally less toxic than its predecessor, cisplatin, but it can still cause significant side effects, such as myelosuppression, nephrotoxicity, and ototoxicity. Careful patient selection, dose optimization, and supportive care are essential to manage these side effects and ensure the safe and effective use of carboplatin in cancer treatment.
9. 항암제 투약 전 약물

Medications administered prior to chemotherapy are an important aspect of cancer treatment. These medications are typically used to prevent or manage the side effects associated with chemotherapy, such as nausea, vomiting, and hypersensitivity reactions. Common pre-medications include antiemetics (to prevent nausea and vomiting), corticosteroids (to reduce inflammation and hypersensitivity), and antihistamines (to prevent allergic reactions). The selection and dosing of these pre-medications are tailored to the specific chemotherapy regimen and the individual patient's needs. Careful management of these pre-medications is crucial to ensure the safe and effective administration of chemotherapy and to optimize the patient's overall treatment experience.
10. 기타 약물

In addition to the chemotherapy drugs and pre-medications discussed, there are a variety of other medications that may be used in the management of cancer patients. These can include supportive care medications, such as pain relievers, anti-anxiety drugs, and sleep aids, as well as medications to manage the side effects of cancer treatments, such as antidiarrheal agents, antiemetics, and growth factors to stimulate blood cell production. The selection and use of these additional medications are based on the individual patient's needs and the specific challenges they face during their cancer treatment. Careful coordination and communication between the healthcare team and the patient are essential to ensure the safe and effective use of these medications and to optimize the patient's overall quality of life during their cancer journey.

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