소뇌의 신경해부학과 기능, 생리학

소개

소뇌의 신경해부학 및 생리학에 대한 발표 ppt 입니다.
소뇌의 신경해부학을 외형적으로 내형적으로 설명하였으며, 소뇌의 기능 및 회로, 생리적 구조에 대하여 자세히 다룬 자료입니다. ppt하단에 내용을 자세히 설명한 주석을 포함하였으며, 읽어보시면 이해가 쉬울것으로 생각됩니다.
참고자료는 아래와 같습니다.
Downey & Darling`s Physiological Basis of Rehabilitation Medicine. 3rd ed., 2001.
Neuroanatomy Through Clinical Cases, 2nd ed. 2010.
Localization in Clinical Neurology. 5th ed., 2006.

목차

Gross anatomy
Macroscopic structure
Cerebellar input
Cerebellar output
Deep cerebellar nucleus
Internal cerebellar circuitries
Cerebrocerebellar and cerebellocerebral circuitries
Cerebellar physiology

본문내용

External Appearance
Embryonic origin :
Rhombic lip
Thickening along the superior margin of 4th ventricle
Sensory information to cerebellum
Automatic coordination and control of somatic motor function
Midline vermis, paravermal of intermediate zone and 2 lateral hemisphere
150g, and 1000cm2 of surface area in human adult

Cerebellar Peduncle
Superior cerebellar peduncle
Dicussate in the midbrain
Mainly output
Middle cerebellar peduncle
Connect with pons
Mainly input
Inferior cerebellar peduncle
Connect with medullar
Mainly input

Macroscopic Structure
Cerebellar cortex : highly convoluted layer of gray matter
Folia (leaf) : narrow leaf-like lamina (gyrus of cortex)
Whit matter : afferent and efferent tracts
4 pairs of deep cerebellar nuclei
Dentate nucleus
Emboliform nucleus
Globuse nucleus
(2+3 = interposed nucleus)
4. Fastigial nucleus

<중 략>

Cerebellar Cortex ? Neuronal Discharge
Stimulation of climbing fiber system
Intense and prolonged reaction of Purkinje cell with initial large spike followed by several smaller ones (complex EPSP)
Prolonged IPSP
Mechanism of complex spike
Repetitive discharge from inferior olive neuron because of axon collateral within inferior olive
Intrinsic property of membrane of Purkinje cell
IPSP
Stimultaneous activation of stellate and basket cell by the climbing fiber
Inhibition of Purkinje cell by feedforward pathway

Cerebellar Cortex ? Neuronal Discharge
Facilitation of Golgi cell by mossy and climbing fiber
Inhibition of granule cell
Inhibition of Purkinje cell
Disinhibition of Purkinje cell

참고자료

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