Cervical Cancer

소개

Cervical Cancer와 관련된 전반적인 내용 진단 평가 및 치료법

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Introduction
Most common gynecologic neoplasm in the United Stats
Preventable
long preinvasive state
Cervical cytology screening programs
effective treatment for preinvasive lesions
The initiating event in cervical dysplasia and carcinogenesis is infection with HPV
Evaluations
Symptoms
Vaginal (postcoital) bleeding m/c
Malodorous vaginal discharge
Weight loss
Obstructive uropathy
Supraclavicular and groin lymph nodes palpation -metastasis
Rectal examination size
Cervical Bx (obvious growth present)
-> colposcopy (gross findings 없다면)
-> cervical conization (if cannot be diagnosed)

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Chronic effects
Bladder atony in 3%
Radiation fibrosis of bowel and bladder in 6%8%
Applicability
Best candidates are younger than 65 years of age, <200 lb, and in good health
All patients are potential candidates
Surgical mortality
1%
1% (from pulmonary embolism during intracavitary therapy)
Recurrent Cervical cancer
Treatment depends on the mode of primary therapy and the site of recurrence
Initially treated with surgery -> consider radiation
과거 radiation -> consider surgery
Limited to patients with central pelvic disease
Chemotherapy is palliative only and is reserved for patients who are not considered curable by other two modalities.
Thank you

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