항노화 화장품 소재로서의 알로에 베라 추출물에 관한 연구 (A Study on the Aloe vera extract as the Anti-againg Cosmetic Ingredient)

서지정보

· 발행기관 : 한국미용학회
· 수록지 정보 : 한국미용학회지 / 19권 / 5호 / 931 ~ 936페이지
· 저자명 : 윤미연, 표영희

초록

Aloe vera (Aloe barbadensis Miller) is internationally used as a major functional health food or ingredient of pharmaceuticals or cosmetics. It is also the most widely used natural ingredient, and its uses include purgatives, treatment of wounds and burns, and antiinflammatory drugs. Therefore, the aim of this study was to use aqueous extracts of aloe vera to measure antioxidation using DPPH related to activation of skin physiology, prevention of activation of hyaluronidase, elastase and collagenase, and creation of elastin and collagen to examine anti-aging effects as part of a study on the physiology activation of aloe vera, which is already known for its safety and functionality. NR solution was used to measure cytotoxicity and examine cell safety of the aloe vera extracts before each experiment.
No cytotoxicity was found for concentrations of 1, 10 and 100 g/ml. Radical scavenging activity was found when measuring antioxidation through DPPH, and there was 26.1% radical scavenging at the top concentration of 100 g/ml. The results showed prevention of hyaluronidase, elastase and MMP-1 activation. In addition, collagen creation increased slightly according to concentration,and elastin increased greatly by more than 50%. The results of this study indicate that aloe vera extract is a natural substance with various skin physiology activating effects, and can be applied as an ingredient of functional anti-aging cosmetics with antioxidizing,wrinkle-improving and skin elasticity effects.

영어초록

Aloe vera (Aloe barbadensis Miller) is internationally used as a major functional health food or ingredient of pharmaceuticals or cosmetics. It is also the most widely used natural ingredient, and its uses include purgatives, treatment of wounds and burns, and antiinflammatory drugs. Therefore, the aim of this study was to use aqueous extracts of aloe vera to measure antioxidation using DPPH related to activation of skin physiology, prevention of activation of hyaluronidase, elastase and collagenase, and creation of elastin and collagen to examine anti-aging effects as part of a study on the physiology activation of aloe vera, which is already known for its safety and functionality. NR solution was used to measure cytotoxicity and examine cell safety of the aloe vera extracts before each experiment.
No cytotoxicity was found for concentrations of 1, 10 and 100 g/ml. Radical scavenging activity was found when measuring antioxidation through DPPH, and there was 26.1% radical scavenging at the top concentration of 100 g/ml. The results showed prevention of hyaluronidase, elastase and MMP-1 activation. In addition, collagen creation increased slightly according to concentration,and elastin increased greatly by more than 50%. The results of this study indicate that aloe vera extract is a natural substance with various skin physiology activating effects, and can be applied as an ingredient of functional anti-aging cosmetics with antioxidizing,wrinkle-improving and skin elasticity effects.

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