국내 유통품 남강활 및 북강활의 HPLC 성분패턴 비교분석 (Comparative Analysis of HPLC Component Patterns of Angelica reflexa roots by two cultivation types distributed in Korea)

서지정보

· 발행기관 : 한약정보연구회
· 수록지 정보 : 한약정보연구회지(韓藥情報硏究會誌) / 8권 / 2호 / 205 ~ 213페이지
· 저자명 : 김효선, 서영혜, 이아영, 류승목, 최고야, 문병철, 이준

초록

As a part of a comparative study of the chemical components of A. reflexa roots by two cultivation types, Namganghwal and Bukganghwal, which are the same taxonomic origin but are classified according to their cultivation method and ecological type, seven samples of Namganghwal and six samples of Bukganghwal, currently distributed in Korea, were collected and their chemical components were identified by high-performance liquid chromatography with photodiode array detector (HPLC-PDA). Through this study, a total of ten major peaks were detected, and eight of them were identified as chlorogenic acid (1), ferulic acid (4), oxypeucedanin hydrate (5), bisabolangelone (6), oxypeucedanin (7), imperatorin (8), osthole (9), and isoimperatorin (10), respectively. Based on these analyses, as a result of comparing the component patterns of Namganghwal and Bukganghwal, the major component patterns of the two groups showed significant differences. In particular, oxypeucedanin (7), imperatorin (8), and isoimperatorin (10) were detected with higher levels in Namganghwal samples, and ferulic acid (4) was detected with higher levels in Bukganghwal samples. In this study, we report the analysis method of chemical components of A. reflexa roots, identification of the components, and comparative analysis of the component patterns of two types of A. reflexa roots, Namganghwal and Bukganghwal.

영어초록

As a part of a comparative study of the chemical components of A. reflexa roots by two cultivation types, Namganghwal and Bukganghwal, which are the same taxonomic origin but are classified according to their cultivation method and ecological type, seven samples of Namganghwal and six samples of Bukganghwal, currently distributed in Korea, were collected and their chemical components were identified by high-performance liquid chromatography with photodiode array detector (HPLC-PDA). Through this study, a total of ten major peaks were detected, and eight of them were identified as chlorogenic acid (1), ferulic acid (4), oxypeucedanin hydrate (5), bisabolangelone (6), oxypeucedanin (7), imperatorin (8), osthole (9), and isoimperatorin (10), respectively. Based on these analyses, as a result of comparing the component patterns of Namganghwal and Bukganghwal, the major component patterns of the two groups showed significant differences. In particular, oxypeucedanin (7), imperatorin (8), and isoimperatorin (10) were detected with higher levels in Namganghwal samples, and ferulic acid (4) was detected with higher levels in Bukganghwal samples. In this study, we report the analysis method of chemical components of A. reflexa roots, identification of the components, and comparative analysis of the component patterns of two types of A. reflexa roots, Namganghwal and Bukganghwal.

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