HPLC를 이용한 국내 유통품 황금의 성분패턴 비교 연구 (Comparative Study on the Component Pattern of Scutellaria baicalensis roots distributed in Korea using HPLC)

서지정보

· 발행기관 : 한약정보연구회
· 수록지 정보 : 한약정보연구회지(韓藥情報硏究會誌) / 8권 / 2호 / 233 ~ 242페이지
· 저자명 : 김효선, 서영혜, 양선규, 서창섭, 이아영, 류승목, 최고야, 문병철, 이준

초록

This study compares and analyzes the difference in components between the two types of Scutellaria baicalensis roots according to morphological discrimination. The roots of S. baicalensis are divided into two types, Jo-geum and Go-geum, according to the harvest time and shape, and these have been used for different therapeutic purposes. But currently, comparative studies on the chemical constituents and efficacy of them are insufficient. In this study, a total of 14 samples of S. baicalensis roots, distributed in Korea, were collected and divided into two types (Jo-geum and Go-geum) through morphological discrimination. Their main four components, baicalin (1), wogonoside (2), baicalein (3), and wogonin (4), were identified and analyzed using high-performance liquid chromatography with a photodiode array detector. As a result, the signal of wogonin (4) showed a significant difference between the two types. A relatively higher level of signals was detected in the Go-geum samples regardless of the origin. In addition, these component patterns were consistent with the morphological discrimination results.

영어초록

This study compares and analyzes the difference in components between the two types of Scutellaria baicalensis roots according to morphological discrimination. The roots of S. baicalensis are divided into two types, Jo-geum and Go-geum, according to the harvest time and shape, and these have been used for different therapeutic purposes. But currently, comparative studies on the chemical constituents and efficacy of them are insufficient. In this study, a total of 14 samples of S. baicalensis roots, distributed in Korea, were collected and divided into two types (Jo-geum and Go-geum) through morphological discrimination. Their main four components, baicalin (1), wogonoside (2), baicalein (3), and wogonin (4), were identified and analyzed using high-performance liquid chromatography with a photodiode array detector. As a result, the signal of wogonin (4) showed a significant difference between the two types. A relatively higher level of signals was detected in the Go-geum samples regardless of the origin. In addition, these component patterns were consistent with the morphological discrimination results.

참고자료

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