단일 기관에서의 초극소 저출생 체중아의 치료 성적 (2003-2006) (Outcomes of Extremely Low Birth Weight Infants at the Asan Medical Center between 2003 and 2006)

서지정보

· 발행기관 : 대한신생아학회
· 수록지 정보 : Neonatal medicine / 15권 / 2호 / 123 ~ 133페이지
· 저자명 : 박미림, 이병섭, 김기수, 피수영, 김애란

초록

Purpose : The purpose of this study was to determine the outcomes of extremely low
birth weight infants (ELBWI) who were born at the Asan Medical Center and evaluate the
recent status of neonatal intensive care and associated problems.
Methods : We retrospectively evaluated 120 inborn ELBWI who were admitted to the
NICU of the Asan Medical Center between 2003 and 2006. The survival rate, neurodevelopmental
outcomes, maternal and infant factors, and infant mordibities were evaluated and the
relationships with survival and catch-up growth were investigated.
Results : The survival rate of the ELBWI was 82% at a mean gestational age of 27＋2
weeks, and with a mean birth weight of 801.3±129.0 g. The duration of hospitalization was
85.7±27.2 days, the duration of O2 use was 43.9±35.4 days, and the duration of ventilatory
support was 20.9±20.9 days among the survivors. The incidence of respiratory distress syndrome,
chronic lung disease, severe intraventricular hemorrhage, and periventricular leukomalacia
were 41.8%, 61.2%, 3%, and 4%, respectively. The mean mental developmental index
and psychomotor development index of Bailey Scales of Infant Development (II) at follow-up
were 83.4±18.2 and 83.3±20.3, respectively. Among the infants who had >18 months of
follow-up, 50.8% had catch-up growth at 12 months.
Conclusion : The survival rate of ELBWI has improved; however, the morbidities remain
high, thus indicating further efforts must be implemented to reduce morbidity and improve
neurodevelopmental outcomes.

영어초록

Purpose : The purpose of this study was to determine the outcomes of extremely low
birth weight infants (ELBWI) who were born at the Asan Medical Center and evaluate the
recent status of neonatal intensive care and associated problems.
Methods : We retrospectively evaluated 120 inborn ELBWI who were admitted to the
NICU of the Asan Medical Center between 2003 and 2006. The survival rate, neurodevelopmental
outcomes, maternal and infant factors, and infant mordibities were evaluated and the
relationships with survival and catch-up growth were investigated.
Results : The survival rate of the ELBWI was 82% at a mean gestational age of 27＋2
weeks, and with a mean birth weight of 801.3±129.0 g. The duration of hospitalization was
85.7±27.2 days, the duration of O2 use was 43.9±35.4 days, and the duration of ventilatory
support was 20.9±20.9 days among the survivors. The incidence of respiratory distress syndrome,
chronic lung disease, severe intraventricular hemorrhage, and periventricular leukomalacia
were 41.8%, 61.2%, 3%, and 4%, respectively. The mean mental developmental index
and psychomotor development index of Bailey Scales of Infant Development (II) at follow-up
were 83.4±18.2 and 83.3±20.3, respectively. Among the infants who had >18 months of
follow-up, 50.8% had catch-up growth at 12 months.
Conclusion : The survival rate of ELBWI has improved; however, the morbidities remain
high, thus indicating further efforts must be implemented to reduce morbidity and improve
neurodevelopmental outcomes.

참고자료

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