비만의 양면성: 강원도 중장년 여성의 대사증후군과 골다공증 (Two Sides of Obesity: Metabolic Syndrome and Osteoporosis in Elderly Women, Gangwon-do, Korea)

서지정보

· 발행기관 : 한국보건교육건강증진학회
· 수록지 정보 : 보건교육건강증진학회지 / 31권 / 1호 / 13 ~ 26페이지
· 저자명 : 장성옥, 이성화, 이종석

초록

Objectives: This study aimed to assess whether metabolic syndrome (MS) is related to osteoporosis and investigate the association betweenthe MS components and bone mineral density (BMD). Methods: We conducted a cross-sectional study for 4,365 women aged over 50years who completed health examination from 2008 to 2012 in Korea Association of Health Promotion Gangwon Branch. Height, bodyweight, waist circumference, blood pressure, fasting plasma glucose, serum lipid profiles, and BMD were measured. Results: Obesitymeasured as body mass index (BMI) was detrimental to all of the MS components but positively correlated with BMD at three skeletalsites (lumbar spine, femoral neck, and total hip). There were no significant differences in the MS prevalence between women withoutosteoporosis and those with osteoporosis. In age-adjusted analysis, women with MS had significantly higher BMD at three sites whencompared to those without MS. After adjusting for BMI and age, these significances disappeared, such that MS was not associated withhigher BMD. Conclusions: Our findings indicate that obesity increases the risk of MS whereas underweight increases that of osteoporosis.
The association between MS and higher BMD was explained by the higher BMI in those with MS. MS may not be associated withosteoporosis.

영어초록

Objectives: This study aimed to assess whether metabolic syndrome (MS) is related to osteoporosis and investigate the association betweenthe MS components and bone mineral density (BMD). Methods: We conducted a cross-sectional study for 4,365 women aged over 50years who completed health examination from 2008 to 2012 in Korea Association of Health Promotion Gangwon Branch. Height, bodyweight, waist circumference, blood pressure, fasting plasma glucose, serum lipid profiles, and BMD were measured. Results: Obesitymeasured as body mass index (BMI) was detrimental to all of the MS components but positively correlated with BMD at three skeletalsites (lumbar spine, femoral neck, and total hip). There were no significant differences in the MS prevalence between women withoutosteoporosis and those with osteoporosis. In age-adjusted analysis, women with MS had significantly higher BMD at three sites whencompared to those without MS. After adjusting for BMI and age, these significances disappeared, such that MS was not associated withhigher BMD. Conclusions: Our findings indicate that obesity increases the risk of MS whereas underweight increases that of osteoporosis.
The association between MS and higher BMD was explained by the higher BMI in those with MS. MS may not be associated withosteoporosis.

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