瓊玉膏가 영양소 결핍으로 유도한 성장장애 흰쥐의 성장 및 학습효과에 미치는 영향 (Effects of Kyungohkgo(Qiong yu gao) on Growth and Learning Ability in Growth Deficiency Rat with Insufficient Nutrition Diet)

서지정보

· 발행기관 : 한방재활의학과학회
· 수록지 정보 : 한방재활의학과학회지 / 18권 / 2호 / 97 ~ 109페이지
· 저자명 : 한석훈, 차윤엽, 이은

초록

Objectives :
Effects of Kyungohkgo(Qióng yù gào) on intellectual development and learning ability were investigated growth and intellectual impairment rat with insufficient nutrition diet.
Methods :
We divided male Sprague-Dawley rats into 4 groups(A, B, C, D). They were normal group(A), growth deficiency rat with insufficient nutrition diet group(B), growth deficiency rat with 0.1% Kyungohkgo(Qióng yù gào) group(C) and growth deficiency rat with 0.2% Kyungohkgo(Qióng yù gào) group(D). They were administered for 5 weeks. We measured body weight, serum growth hormone, insulin-like growth factor and thyroid stimulating hormone, RBC, concentration of Hb and PCV ratio, total WBC and its composition, the values of plasma glutamic oxaloacetic transaminase(GOT) and glutamic pyruvic transaminase(GPT) activities and morris water maze test in escape distance, escape time and escape speed.
Results :
1. Body weight showed a tendency to increase in the Kyungohkgo(Qióng yù gào) groups and 0.2% Kyungohkgo(Qióng yù gào) group showed significantly different than control groups.
2. Serum growth hormone, insulin-like growth factor and thyroid stimulating hormone showed a tendency to increase in Kyungohkgo(Qióng yù gào) groups, however these values showed no significantly different.
3. About the counts of RBC, 0.1% and 0.2% Kyungohkgo(Qióng yù gào) groups showed significantly different than control groups. Concentration of Hb was higher than control group in Kyungohkgo(Qióng yù gào) groups. And 0.2% Kyungohkgo(Qióng yù gào) group showed significantly different than control groups in PCV ratio.
4. The counts of total WBC and its composition showed no significantly different in all treatment groups.
5. The values of plasma glutamic oxaloacetic transaminase(GOT) and glutamic pyruvic transaminase(GPT) activities showed no significantly different in all treatment groups.
6. In the morris water maze test, in escape distance and escape speed, Kyungohkgo(Qióng yù gào) groups showed no significantly different than control group. But Kyungohkgo(Qióng yù gào) groups showed the increasing tendency.
Conclusions :
So Kyungohkgo(Qióng yù gào) have an effect of promoting growth of rats and might be effect to treat various kinds of growth delay in children.

영어초록

Objectives :
Effects of Kyungohkgo(Qióng yù gào) on intellectual development and learning ability were investigated growth and intellectual impairment rat with insufficient nutrition diet.
Methods :
We divided male Sprague-Dawley rats into 4 groups(A, B, C, D). They were normal group(A), growth deficiency rat with insufficient nutrition diet group(B), growth deficiency rat with 0.1% Kyungohkgo(Qióng yù gào) group(C) and growth deficiency rat with 0.2% Kyungohkgo(Qióng yù gào) group(D). They were administered for 5 weeks. We measured body weight, serum growth hormone, insulin-like growth factor and thyroid stimulating hormone, RBC, concentration of Hb and PCV ratio, total WBC and its composition, the values of plasma glutamic oxaloacetic transaminase(GOT) and glutamic pyruvic transaminase(GPT) activities and morris water maze test in escape distance, escape time and escape speed.
Results :
1. Body weight showed a tendency to increase in the Kyungohkgo(Qióng yù gào) groups and 0.2% Kyungohkgo(Qióng yù gào) group showed significantly different than control groups.
2. Serum growth hormone, insulin-like growth factor and thyroid stimulating hormone showed a tendency to increase in Kyungohkgo(Qióng yù gào) groups, however these values showed no significantly different.
3. About the counts of RBC, 0.1% and 0.2% Kyungohkgo(Qióng yù gào) groups showed significantly different than control groups. Concentration of Hb was higher than control group in Kyungohkgo(Qióng yù gào) groups. And 0.2% Kyungohkgo(Qióng yù gào) group showed significantly different than control groups in PCV ratio.
4. The counts of total WBC and its composition showed no significantly different in all treatment groups.
5. The values of plasma glutamic oxaloacetic transaminase(GOT) and glutamic pyruvic transaminase(GPT) activities showed no significantly different in all treatment groups.
6. In the morris water maze test, in escape distance and escape speed, Kyungohkgo(Qióng yù gào) groups showed no significantly different than control group. But Kyungohkgo(Qióng yù gào) groups showed the increasing tendency.
Conclusions :
So Kyungohkgo(Qióng yù gào) have an effect of promoting growth of rats and might be effect to treat various kinds of growth delay in children.

참고자료

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