Differences of Garlic Powder Ingestion and Exercise Training on Blood Lipids, MDA and SOD in Rats

서지정보

· 발행기관 : 한국생명과학회
· 수록지 정보 : 생명과학회지 / 19권 / 10호 / 1337 ~ 1345페이지
· 저자명 : 전병덕, 김진하, 류승필

초록

This study investigated the effect of exercise training and garlic powder ingestion on blood lipids and antioxidants activity in rats. Twenty-eight male Sprague Dawley rats were fed a high-fat diet with or without garlic powder (500 mg/kg) for four weeks as grouped in control (CON), exercise (EXE), garlic (GAR), and garlic + exercise training (GAREXE), respectively. EXE and GAREXE were trained on the treadmill for the same periods. Weight of fats (mesentery, perirenal, and epididymal) were weighed and blood glucose, triglycerides (TG), total cholesterol (TC), and high density lipoprotein-cholesterol (HDL-C) were analyzed and low density lipoprotein-cholesterol (LDL-C) was calculated. Malondialdehyde (MDA) and superoxide dismutase (SOD) for lipid peroxidation were analyzed in liver tissue. Body weight in GAREXE was significantly lower in the statistics than that in other groups (p＜0.05), and the volume of fat in GAR and GAREXE was also much lower (p＜0.05). Blood glucose was significantly lower in EXE and GAR (p＜0.05), however, there was no effect of exercise training. Blood TG was lower in GAR and GAREXE (p＜0.05), however, there was no effect of exercise training. HDL-C was significantly improved in EXE and GAR compared to CON (p＜0.05), and GAREXE was higher than EXE (p＜0.05). MDA content was considerably lower in GAREXE compared to EXE (p＜0.05), and SOD activity was much higher in other groups compared to CON (p＜0.05). In addition, GAREXE was significantly higher than EXE and GAR, thus there was significant increase when a garlic diet was carried out together with exercise (p＜0.05). These results suggested that garlic powder ingestion during the training periods had a beneficial effect of lowering glucose and enhancing blood lipids profiles. Moreover, it also has antioxidant effects, which means that it could possibly suppress aging. It is necessary to inspect various effects of garlic with a variety of research methods regarding sampling process, production process, intake method, etc.

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