십전대보탕의 장기보관 중 품질변화 (Quality Variation of Sibjeondaebotang according to Long-term Storage)

서지정보

· 발행기관 : 한국생약학회
· 수록지 정보 : 생약학회지 / 47권 / 4호 / 374 ~ 380페이지
· 저자명 : 김애경, 이춘영, 황광호, 이영종, 김수진, 이영주, 이현경, 이새람, 김일영, 이정미, 유인실, 정권

초록

The purpose of this study was to evaluate of quality variation of Sibujeondaebotang according to storage period and temperature (5 and 25oC) Identificaion test, pH, specific gravity, heavy metal, microbial limit test and glycyrrhizic acid, paeoniflorin content of Sibjeondaebotang were performed during 12 months. The significant change was not shown on identificaion test, specific gravity, microbial limit test under long term storage and the result suited a safe level standards of ‘Korean National Standard of Traditional Medicinal (Herbal and Botanical) Materials - “Sibjeondaebotang”’. The test of pH showed meaningful changes between two storage temperature (5 and 25oC) according to increasing storage period. The contents of glycyrrhizic acid and paeoniflorin had no relation with storage temperature(5oC, 25oC) but it showed a tendency to decrease according to the length of storage period. We predicted shelf-life of glycyrrhizic acid and paeoniflorin at storgae temperature(5 and 25oC) as about 6 and 3 months, respecttively. Therefore considering glycyrrhizic acid and paeoniflorin, sibjeondaebotang is determined to be in good condition within 3 months, regardless of the room temperature and refrigerated temperature. We were expected to serve as a basis for the guideline of medication counseling sibjeondaebotang.

영어초록

The purpose of this study was to evaluate of quality variation of Sibujeondaebotang according to storage period and temperature (5 and 25oC) Identificaion test, pH, specific gravity, heavy metal, microbial limit test and glycyrrhizic acid, paeoniflorin content of Sibjeondaebotang were performed during 12 months. The significant change was not shown on identificaion test, specific gravity, microbial limit test under long term storage and the result suited a safe level standards of ‘Korean National Standard of Traditional Medicinal (Herbal and Botanical) Materials - “Sibjeondaebotang”’. The test of pH showed meaningful changes between two storage temperature (5 and 25oC) according to increasing storage period. The contents of glycyrrhizic acid and paeoniflorin had no relation with storage temperature(5oC, 25oC) but it showed a tendency to decrease according to the length of storage period. We predicted shelf-life of glycyrrhizic acid and paeoniflorin at storgae temperature(5 and 25oC) as about 6 and 3 months, respecttively. Therefore considering glycyrrhizic acid and paeoniflorin, sibjeondaebotang is determined to be in good condition within 3 months, regardless of the room temperature and refrigerated temperature. We were expected to serve as a basis for the guideline of medication counseling sibjeondaebotang.

참고자료

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