후천성 아교질종에 대한 임상적 고찰 (Study of the Clinical Features of Acquired Collagenoma)

서지정보

· 발행기관 : 대한피부과학회
· 수록지 정보 : 대한피부과학회지 / 52권 / 11호 / 776 ~ 782페이지
· 저자명 : 나찬호, 송상현, 김민성, 신봉석

초록

Background: A collagenoma or connective tissue nevus of the collagen type is a hamartoma consisting predominantlyof collagen. Collagenomas are divided into the inherited and acquired types. The acquired forms includeeruptive and isolated collagenoma. However, few studies have assessed the characteristics of patients with acquiredcollagenoma.
Objective: The aim of this study was to analyze the clinical characteristics of patients with acquired collagenoma.
Methods: We reviewed the medical records and clinical photographs of 23 patients who had been diagnosedhistopathologically with acquired collagenoma by biopsy during the last 12 years, from January 2002 to December2013. In addition, 11 cases of eruptive or isolated collagenomas previously reported in the Korean literature wereadded.
Results: In total, 34 cases of acquired collagenoma were assessed. Of the 34 cases, 53% were men and 47% werewomen. The mean age at diagnosis was 20.0 years for the patients with eruptive collagenoma and 29.1 years forthe patients with isolated collagenoma. In the cases of eruptive collagenoma, multiple, flesh-colored or whitishpapules on the trunk were predominant. On the other hand, in the cases of isolated collagenoma, solitary,flesh-colored plaques on the palms or soles were common features. Collagenomas in most cases were asymptomatic(79.4%). However, some patients with collagenomas had other symptoms such as tenderness or pruritus. There wasno traumatic history in any case.
Conclusion: Our study showed that the clinical features of patients with acquired collagenoma share manysimilarities with those in previously reported studies, with some differences. This study is expected to help usunderstand and obtain more information on the clinical diagnosis of acquired collagenoma.

영어초록

Background: A collagenoma or connective tissue nevus of the collagen type is a hamartoma consisting predominantlyof collagen. Collagenomas are divided into the inherited and acquired types. The acquired forms includeeruptive and isolated collagenoma. However, few studies have assessed the characteristics of patients with acquiredcollagenoma.
Objective: The aim of this study was to analyze the clinical characteristics of patients with acquired collagenoma.
Methods: We reviewed the medical records and clinical photographs of 23 patients who had been diagnosedhistopathologically with acquired collagenoma by biopsy during the last 12 years, from January 2002 to December2013. In addition, 11 cases of eruptive or isolated collagenomas previously reported in the Korean literature wereadded.
Results: In total, 34 cases of acquired collagenoma were assessed. Of the 34 cases, 53% were men and 47% werewomen. The mean age at diagnosis was 20.0 years for the patients with eruptive collagenoma and 29.1 years forthe patients with isolated collagenoma. In the cases of eruptive collagenoma, multiple, flesh-colored or whitishpapules on the trunk were predominant. On the other hand, in the cases of isolated collagenoma, solitary,flesh-colored plaques on the palms or soles were common features. Collagenomas in most cases were asymptomatic(79.4%). However, some patients with collagenomas had other symptoms such as tenderness or pruritus. There wasno traumatic history in any case.
Conclusion: Our study showed that the clinical features of patients with acquired collagenoma share manysimilarities with those in previously reported studies, with some differences. This study is expected to help usunderstand and obtain more information on the clinical diagnosis of acquired collagenoma.

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