일부 어린이 해열·진통제의 유치 법랑질 부식효과 (Effects of the Enamel Erosion Caused by Certain Antipyretic and Analgesic Medicines for Children)

서지정보

· 발행기관 : 한국치위생과학회
· 수록지 정보 : 치위생과학회지 / 16권 / 3호 / 235 ~ 241페이지
· 저자명 : 천수경, 정문진, 안용순, 이예진, 고미경, 정순정, 임도선

초록

This study was conducted to provide basic understanding regarding possible enamel erosion by three kinds of first-aid antipyretic and analgesic medicines over a period of time, with comparison and analysis of the resulting deciduous teeth surface and microhardness changes. The analysis was performed using energy dispersive X-ray spectroscopy (EDX) and scanning electron microscope (SEM) to examine the surface erosion and changes. The Kruskal-Wallis test show differences in surface erosion and changes after 3, 5 and 8 days of treatment as well as before and after the treatment in each group. According to the results, there was no significant difference in the early deciduous teeth enamel surface microhardness (p＞0.01). However there were signigicant changes after 3, 5, and 8 days (p＜0.01). Calcim (Ca) and phosphorous (P) analysis using EDX showed significant differences in the enamel characteristics according to each tissue area after 8 days (p＜0.05), but there was no significant difference in any of the areas for P content (p＞0.05). In the surface observation with the SEM treatment with Children’s TylenolⓇ tablet, which has the lowest pH, looked the roughest, followed by Brufen syrup for children and Children's TylenolⓇ suspension. Based on these results, it should be considered that antipyretic and analgesic medicines for children, which have lower pH values, may cause tooth erosion. Hence, it is necessary to give special attention to oral hygiene in young children or infants by brushing their teeth after such drugs are administered.

영어초록

This study was conducted to provide basic understanding regarding possible enamel erosion by three kinds of first-aid antipyretic and analgesic medicines over a period of time, with comparison and analysis of the resulting deciduous teeth surface and microhardness changes. The analysis was performed using energy dispersive X-ray spectroscopy (EDX) and scanning electron microscope (SEM) to examine the surface erosion and changes. The Kruskal-Wallis test show differences in surface erosion and changes after 3, 5 and 8 days of treatment as well as before and after the treatment in each group. According to the results, there was no significant difference in the early deciduous teeth enamel surface microhardness (p＞0.01). However there were signigicant changes after 3, 5, and 8 days (p＜0.01). Calcim (Ca) and phosphorous (P) analysis using EDX showed significant differences in the enamel characteristics according to each tissue area after 8 days (p＜0.05), but there was no significant difference in any of the areas for P content (p＞0.05). In the surface observation with the SEM treatment with Children’s TylenolⓇ tablet, which has the lowest pH, looked the roughest, followed by Brufen syrup for children and Children's TylenolⓇ suspension. Based on these results, it should be considered that antipyretic and analgesic medicines for children, which have lower pH values, may cause tooth erosion. Hence, it is necessary to give special attention to oral hygiene in young children or infants by brushing their teeth after such drugs are administered.

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