운동 강도에 따른 혈중 세로토닌과 전염증성 사이토카인 변화에 관한 연구 (The Study of Blood Serotonin and Pro-Inflammatory Cytokine Secretion Following Different Exercise Intensity)

서지정보

· 발행기관 : 한국사회체육학회
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· 저자명 : 김정규

초록

The purpose of this study was examine the effects of differenet xercise intensities on blood serotonin and pro-inflammatory cytokine. There is strong evidence for conneciotn between pro-inflammatory cytokine and depression. Also, imbalance in the production and transmissiono f serotonin is commonly observed in the central nervous system in major depression. All subjects performed running test at two different kinds of exercise intensities, 50% V·O2max and 85% V·O2max, respectively. Blood-sampling was carried out 4 times(rest, end of exercise, 1h post and 4h post exercise) for analysing blood serotonin, TNF-α, IL-1β, and IL-6. The results of study showd that the concentrations of serum serotonin, IL-6 and TNF-α were influenced by exercise intensity.
So this study indicated that high intensity exercise than low-intensity exercise maybe has more positive effects on a person with depression and exercise intensity could be major factors of influence turnover rate of serotonin and pro-inflammatory cytokine metabolism.
In summary, further studies are required to enable more definiivte and scientific conclusions, particularly in patients suffering from depression.

영어초록

The purpose of this study was examine the effects of differenet xercise intensities on blood serotonin and pro-inflammatory cytokine. There is strong evidence for conneciotn between pro-inflammatory cytokine and depression. Also, imbalance in the production and transmissiono f serotonin is commonly observed in the central nervous system in major depression. All subjects performed running test at two different kinds of exercise intensities, 50% V·O2max and 85% V·O2max, respectively. Blood-sampling was carried out 4 times(rest, end of exercise, 1h post and 4h post exercise) for analysing blood serotonin, TNF-α, IL-1β, and IL-6. The results of study showd that the concentrations of serum serotonin, IL-6 and TNF-α were influenced by exercise intensity.
So this study indicated that high intensity exercise than low-intensity exercise maybe has more positive effects on a person with depression and exercise intensity could be major factors of influence turnover rate of serotonin and pro-inflammatory cytokine metabolism.
In summary, further studies are required to enable more definiivte and scientific conclusions, particularly in patients suffering from depression.

참고자료

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