임신 전 체질량지수와 사산, 조산 및 저출생제중아 출산 위험 (Prepregnancy Body Mass Index and the Risk of Stillbirth, Preterm Birth, and Low Birth Weight)

서지정보

· 발행기관 : 한국모자보건학회
· 수록지 정보 : 한국모자보건학회지 / 16권 / 1호 / 67 ~ 79페이지
· 저자명 : 전병화, 오희철, 한영자, 이상욱

초록

Objective: To explore whether women with overweight or underweight before pregnancy would be at higher risk of adverse birth outcomes.
Methods: A retrospective study was conducted on 41,975 mothers who received health examination in 1997, and delivered a singleton live baby in 1999 or a singleton stillbirth from 1999 to 2000. Odds ratio (OR) and 95% confidence interval (CI) for stillbirth, preterm birth, and low birth weight (LBW) according to pre-pregnancy body mass index (BMI, kg/m2) by 3 or 7 groups, were adjusted for maternal age at delivery, socio-economic status, diabetes and parity using logistic regression model.
Results: The adjusted ORs for preterm birth and LBW were 1.39 (95% CI 1.09~1.79), and 1.38 (95% CI 1.05~1.81) in overweight (BMI≥25) women compared to normal weight women (BMI 18.5~24.9), and 2.37 (95% CI 1.60~3.52) and 1.56 (95% CI 0.94~2.59) in obese (BMI≥27.5) women compared to women with middle normal weight (BMI 21~ 22.9), respectively. Obese women had a increased risk on very LBW (OR 6.2, 95% CI 1.99~19.3) compared to middle normal weight women. Moderately to severely thin women (BMI<17) also had a increased risk on LBW (OR 1.65, 95% CI 1.21~2.24) and moderately LBW (OR 1.72, 95% CI 1.26~2.35) compared to middle normal weight women.
Conclusion: Overweight, especially obese women were at higher risk on preterm birth including moderately preterm birth, and very LBW. Moderately thin women also had a increased risk on LBW including moderately LBW. It may be beneficial for women with overweight and moderate to severe thinness to have desirable birth outcomes by weight control such as physical activity and diet control.

영어초록

Objective: To explore whether women with overweight or underweight before pregnancy would be at higher risk of adverse birth outcomes.
Methods: A retrospective study was conducted on 41,975 mothers who received health examination in 1997, and delivered a singleton live baby in 1999 or a singleton stillbirth from 1999 to 2000. Odds ratio (OR) and 95% confidence interval (CI) for stillbirth, preterm birth, and low birth weight (LBW) according to pre-pregnancy body mass index (BMI, kg/m2) by 3 or 7 groups, were adjusted for maternal age at delivery, socio-economic status, diabetes and parity using logistic regression model.
Results: The adjusted ORs for preterm birth and LBW were 1.39 (95% CI 1.09~1.79), and 1.38 (95% CI 1.05~1.81) in overweight (BMI≥25) women compared to normal weight women (BMI 18.5~24.9), and 2.37 (95% CI 1.60~3.52) and 1.56 (95% CI 0.94~2.59) in obese (BMI≥27.5) women compared to women with middle normal weight (BMI 21~ 22.9), respectively. Obese women had a increased risk on very LBW (OR 6.2, 95% CI 1.99~19.3) compared to middle normal weight women. Moderately to severely thin women (BMI<17) also had a increased risk on LBW (OR 1.65, 95% CI 1.21~2.24) and moderately LBW (OR 1.72, 95% CI 1.26~2.35) compared to middle normal weight women.
Conclusion: Overweight, especially obese women were at higher risk on preterm birth including moderately preterm birth, and very LBW. Moderately thin women also had a increased risk on LBW including moderately LBW. It may be beneficial for women with overweight and moderate to severe thinness to have desirable birth outcomes by weight control such as physical activity and diet control.

참고자료

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