해양 유래 한약재의 여드름균에 대한 항균 효능 연구 (Antimicrobial activities of ethanolic extracts of marine resources against Propionibacterium acnes)

서지정보

· 발행기관 : 대한본초학회
· 수록지 정보 : 대한본초학회지 / 25권 / 2호 / 65 ~ 70페이지
· 저자명 : 박숙자, 박찬익, 김상찬

초록

Objectives : Biological activities of marine resources have been rarely evaluated compared with other herbal medicines. In the present study, we aimed to evaluate antimicrobial activities of aqueous and ethanolic extracts of five marine resources(Porphyra tenera, Laminariae Thallus, Sargassum, Ostreae Concha, Maliotidis Concha) against Propionibacterium acnes.
Methods : Aqueous axtracts of five marine resources were prepared by decocting in tenfold tap water for 3 h. Etanolic extracts were obtained by extracting five marine resources with tenfold ethanol for 72 h at room temperature. The zone of growth inhibition and minimum inhibitory concentration (MIC) were determined against P. acnes after incubation for 48 h under anaerobic condition.
Results : Ethanolic extracts of Porphyra tenera exhibited potent antimicrobial effects(MIC 62.5 ㎍/㎖ against KCTC3320, MIC 31.25 ㎍/㎖ against KCTC5527). However, all aqueous extracts tested had no effects on the growth inhibition of P. acnes. In addition, four ethanolic extracts except Porphyra tenera showed little inhibitory effect.
Conclusions : These results indicate that ethanolic extracts of Porphyra tenera has antimicrobial activities against P. acnes and also warrant further development of Porphyra tenera extracts as a natural anti-acne agent.

영어초록

Objectives : Biological activities of marine resources have been rarely evaluated compared with other herbal medicines. In the present study, we aimed to evaluate antimicrobial activities of aqueous and ethanolic extracts of five marine resources(Porphyra tenera, Laminariae Thallus, Sargassum, Ostreae Concha, Maliotidis Concha) against Propionibacterium acnes.
Methods : Aqueous axtracts of five marine resources were prepared by decocting in tenfold tap water for 3 h. Etanolic extracts were obtained by extracting five marine resources with tenfold ethanol for 72 h at room temperature. The zone of growth inhibition and minimum inhibitory concentration (MIC) were determined against P. acnes after incubation for 48 h under anaerobic condition.
Results : Ethanolic extracts of Porphyra tenera exhibited potent antimicrobial effects(MIC 62.5 ㎍/㎖ against KCTC3320, MIC 31.25 ㎍/㎖ against KCTC5527). However, all aqueous extracts tested had no effects on the growth inhibition of P. acnes. In addition, four ethanolic extracts except Porphyra tenera showed little inhibitory effect.
Conclusions : These results indicate that ethanolic extracts of Porphyra tenera has antimicrobial activities against P. acnes and also warrant further development of Porphyra tenera extracts as a natural anti-acne agent.

참고자료

· 없음