최근 10년간 포도알균 열상 피부 증후군의 발생 양상과 관련인자 분석 (Clinical Features and the Associated Factors of Staphylococcal Scalded Skin Syndrome during the Recent 10 Years)

서지정보

· 발행기관 : 대한소아감염학회
· 수록지 정보 : Pediatric Infection and Vaccine / 15권 / 2호 / 152 ~ 161페이지
· 저자명 : 박찬희, 나세린, 조형민, 유은정, 정권, 김은영, 김용욱, 김경심

초록

Purpose : Staphylococcal scalded skin syndrome (4S) is uncommon, but reports of 4S are
on the increase during the recent years. The purpose of this study is to determine the
clinical features and associated factors of 4S during the recent 10 years.
Methods : We retrospectively reviewed the medical records and microbiologic results of 63
patients (27 neonates and 36 children) from January 1998 to December 2007.
Results : Since 2003, the incidence of 4S has increased. The mean age of the patients was
16.3 months and the gender ratio was 1:1. The clinical types of 4S were 38 cases of the
abortive type (60%), 19 cases of the intermediate type (30%) and 6 cases of the generalized
type (10%). The culture results were 36 cases of Methicillin resistant S. aureus (MRSA),
4 cases of Methicillin sensitive S. aureus and 17 cases of no growth. The patients were
treated with semi-synthetic penicillin. For the 9 patients who had MRSA isolated and who
didn't improve with penicillin, they were treated with vancomycin instead of penicillin. All
the patients had no complications. 4S abruptly increased in 2005, and especially in neonates,
due to an MRSA outbreak at a local nursery room. The associated factors of 4S in neonates
were hospitalization (27 cases), including nursery infection in 2005 (18 cases) and
dermatitis (1 case). There was an unknown origin for some children, and the suggested
factors for their infection were community acquired infection (24 cases), atopic dermatitis
(9 cases) and hospitalization (3 cases).
Conclusion : 4S has recently been increasing. The major associated factors of 4S are a
history of hospitalization, an outbreak in a nursery room, atopic dermatitis and community
acquired infection. (Korean J Pediatr Infect Dis 2008;15:152-161)

영어초록

Purpose : Staphylococcal scalded skin syndrome (4S) is uncommon, but reports of 4S are
on the increase during the recent years. The purpose of this study is to determine the
clinical features and associated factors of 4S during the recent 10 years.
Methods : We retrospectively reviewed the medical records and microbiologic results of 63
patients (27 neonates and 36 children) from January 1998 to December 2007.
Results : Since 2003, the incidence of 4S has increased. The mean age of the patients was
16.3 months and the gender ratio was 1:1. The clinical types of 4S were 38 cases of the
abortive type (60%), 19 cases of the intermediate type (30%) and 6 cases of the generalized
type (10%). The culture results were 36 cases of Methicillin resistant S. aureus (MRSA),
4 cases of Methicillin sensitive S. aureus and 17 cases of no growth. The patients were
treated with semi-synthetic penicillin. For the 9 patients who had MRSA isolated and who
didn't improve with penicillin, they were treated with vancomycin instead of penicillin. All
the patients had no complications. 4S abruptly increased in 2005, and especially in neonates,
due to an MRSA outbreak at a local nursery room. The associated factors of 4S in neonates
were hospitalization (27 cases), including nursery infection in 2005 (18 cases) and
dermatitis (1 case). There was an unknown origin for some children, and the suggested
factors for their infection were community acquired infection (24 cases), atopic dermatitis
(9 cases) and hospitalization (3 cases).
Conclusion : 4S has recently been increasing. The major associated factors of 4S are a
history of hospitalization, an outbreak in a nursery room, atopic dermatitis and community
acquired infection. (Korean J Pediatr Infect Dis 2008;15:152-161)

참고자료

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