수면장애와 동반된 임상증상에 따른 심박변이도와 수면 관련 설문간의 상관성 연구 (The Relation of HRV, PSQI and IQ with Symptoms of Insomnia Patients)

서지정보

· 발행기관 : 대한한방신경정신과학회
· 수록지 정보 : 동의신경정신과학회지 / 19권 / 3호 / 143 ~ 170페이지
· 저자명 : 양동호, 오경민, 김보경

초록

Objective : This study was to investigate the relation of what insomnia patients' symptoms
with Heart Rate Variability(HRV), Pittsburgh Sleep Quality Index(PSQI) and Insomnia
Questionaire(IQ).
Methods : For this study, we carried out HRV, PSQI and IQ of 43 patients with insomnia
who have come to Donguei oriental hospital of Donguei university from September 2007 to
May 2008. We studied the relationship HRV with PSQI and IQ. For every symptom, this
study classified the patients as none-symptom, symptom groups and analyzed each group's
HRV, PSQI and IQ.
Result :
1. The rate of xerostomia in female group is significantly higher than male group.
2. P1(hypnagogic time), P3(awakening time), LF has negative correlation with age. The score of
P1(hypnagogic time), P3(awakening time), P4(time of recoverable sleep) in the group whose
age is more than 50 are higher than the group whose age is lesser than 50.
3. The frequency of using hypnotics(P6) in the group whose duration of onset are over 1 year was
significantly higher than the score in the group whose duration of onset were below 1 year.
4. The accompanied symptoms in the group who started sleep disorder after stressor are
higher than the number in the group whose duration of onset were poor-defined.
5. The drinking group have lower rate of anorexia, higher score of P1(hypnagogic time) and
TP than non-drinking group.
6. The score of P-total(general quality of sleep) have negative correlation with NN50, HF, TP
and positive correlation with LF/HF.
7. The score of P1(hypnagogic time) have negative correlation with LF.
8. The score of P5a(frequency of delayed hypnagogue) have positive correlation with LF/HF.
9. The score of P5e(frequency of cough or snoring) have negative correlation with RMSSD.
10. The score of I1a(degree of onset insomnia), I1b(degree of maintenance insomnia) have
negative correlation with NN50, pNN50, HF.
11. The score of I1c(degree of termination insomnia) have negative correlation with RMSSD,
NN50, pNN50, HF, TP and positive correlation with MHR, LF/HF.
12.. The score of P5i(frequecy of night pain), LF/HF in the group with headache are higher
than the group without headache.
13. The score of P5a(frequency of delayed hypnagogue), P5c(frequency of awakening for
urine of stoo)l in the group with xerostomia are higher than the group without
xerostomia.
14. The score of P9(degree of unrecoverable sleep) and I5a(degree of onset insomnia) in the
group with chest discomfort are lower than the group without chest discomfort.
15. The score of P7(frequency of drowsiness for daytime) in the group with palpitation are
lower than the group without palpitation.
16. The score of P5c(frequency of awakening for urine of stool), P5f(frequency of burning
sensation), P5h(frequency of nightmare), I1c(degree of termination insomnia) in the group
with burning sensation of upper trunk are higher than the group without burning
sensation.
17. The score of NN50, pNN50, LF, TP in the group with anorexia are lower than the group
without anorexia.
18. The score of P-total(general quality of sleep), P2(duration for sleep start) in the group
with constipation are higher than the group without constipation.
19. The score of P4(recoverable sleep time) in the group with depression are higher than the
group without depression.
20. In the the group with anxiety, the score of P1(time of hypnagogue), P5a(frequency of
onset insomnia) are lower and the score of I1b(degree of maintenance insomnia),
I4(objective degree of impairment by insomnia) are higher than the group without anxiety.
21. The score of NN50, pNN50, HF, TP in the group with inertia are lower than the group
without inertia.
22. The accompanied symptoms haver posirive correlation with P5f(frequency of burning
sensation), P5h(frequency of nightmare), P5i( frequency of night pain) and LF/HF.
Conclusion : This study provides insights into the complicated relations of the pattern of
sleep disorder with many symptoms such as headache, chest discomfort, depression and any
others. And this study showed that autonomic nervous system have important function in
the regulation of sleep.

영어초록

Objective : This study was to investigate the relation of what insomnia patients' symptoms
with Heart Rate Variability(HRV), Pittsburgh Sleep Quality Index(PSQI) and Insomnia
Questionaire(IQ).
Methods : For this study, we carried out HRV, PSQI and IQ of 43 patients with insomnia
who have come to Donguei oriental hospital of Donguei university from September 2007 to
May 2008. We studied the relationship HRV with PSQI and IQ. For every symptom, this
study classified the patients as none-symptom, symptom groups and analyzed each group's
HRV, PSQI and IQ.
Result :
1. The rate of xerostomia in female group is significantly higher than male group.
2. P1(hypnagogic time), P3(awakening time), LF has negative correlation with age. The score of
P1(hypnagogic time), P3(awakening time), P4(time of recoverable sleep) in the group whose
age is more than 50 are higher than the group whose age is lesser than 50.
3. The frequency of using hypnotics(P6) in the group whose duration of onset are over 1 year was
significantly higher than the score in the group whose duration of onset were below 1 year.
4. The accompanied symptoms in the group who started sleep disorder after stressor are
higher than the number in the group whose duration of onset were poor-defined.
5. The drinking group have lower rate of anorexia, higher score of P1(hypnagogic time) and
TP than non-drinking group.
6. The score of P-total(general quality of sleep) have negative correlation with NN50, HF, TP
and positive correlation with LF/HF.
7. The score of P1(hypnagogic time) have negative correlation with LF.
8. The score of P5a(frequency of delayed hypnagogue) have positive correlation with LF/HF.
9. The score of P5e(frequency of cough or snoring) have negative correlation with RMSSD.
10. The score of I1a(degree of onset insomnia), I1b(degree of maintenance insomnia) have
negative correlation with NN50, pNN50, HF.
11. The score of I1c(degree of termination insomnia) have negative correlation with RMSSD,
NN50, pNN50, HF, TP and positive correlation with MHR, LF/HF.
12.. The score of P5i(frequecy of night pain), LF/HF in the group with headache are higher
than the group without headache.
13. The score of P5a(frequency of delayed hypnagogue), P5c(frequency of awakening for
urine of stoo)l in the group with xerostomia are higher than the group without
xerostomia.
14. The score of P9(degree of unrecoverable sleep) and I5a(degree of onset insomnia) in the
group with chest discomfort are lower than the group without chest discomfort.
15. The score of P7(frequency of drowsiness for daytime) in the group with palpitation are
lower than the group without palpitation.
16. The score of P5c(frequency of awakening for urine of stool), P5f(frequency of burning
sensation), P5h(frequency of nightmare), I1c(degree of termination insomnia) in the group
with burning sensation of upper trunk are higher than the group without burning
sensation.
17. The score of NN50, pNN50, LF, TP in the group with anorexia are lower than the group
without anorexia.
18. The score of P-total(general quality of sleep), P2(duration for sleep start) in the group
with constipation are higher than the group without constipation.
19. The score of P4(recoverable sleep time) in the group with depression are higher than the
group without depression.
20. In the the group with anxiety, the score of P1(time of hypnagogue), P5a(frequency of
onset insomnia) are lower and the score of I1b(degree of maintenance insomnia),
I4(objective degree of impairment by insomnia) are higher than the group without anxiety.
21. The score of NN50, pNN50, HF, TP in the group with inertia are lower than the group
without inertia.
22. The accompanied symptoms haver posirive correlation with P5f(frequency of burning
sensation), P5h(frequency of nightmare), P5i( frequency of night pain) and LF/HF.
Conclusion : This study provides insights into the complicated relations of the pattern of
sleep disorder with many symptoms such as headache, chest discomfort, depression and any
others. And this study showed that autonomic nervous system have important function in
the regulation of sleep.

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