퇴행성 슬관절염 환자에서 근육 내 봉독약침과 피내 봉독약침의 효능 비교연구 (Comparative Study of Effects of ‘Intramuscular Bee Venom Herbal Acupuncture’ and ‘Intracutaneous Bee Venom Herbal Acupuncture’ in Knee Osteoarthritis Patients)

서지정보

· 발행기관 : 대한침구의학회
· 수록지 정보 : Journal of Acupuncture Research / 25권 / 2호 / 151 ~ 164페이지
· 저자명 : 김행범, 이로민, 이민호, 최양식, 김종인, 이윤호, 이재동

초록

Objectives : This study was designed to compare the effects on Korean Western Ontario and McMaster Universities Osteoarthritis Index(KWOMAC), 36-Items Short-Form Health Survey(SF-36), Visual Analog Scale(VAS) and Nine Point Scale between ‘Intramuscular Bee Venom Herbal Acupuncture’ and ‘Intracu- taneous Bee Venom Herbal Acupuncture’ in knee osteoarthritis patients for 4weeks.
Methods : All the voluntary subject were diagnosed as knee osteoarthritis. Patients were randomly assigned either to two groups : Intramuscular bee venom herbal acupuncture treatment group(IM-BV group) or Intracutaneous bee venom herbal acupuncture treatment group(IC-BV group).
The IM-BV group received bee venom herbal acupuncture intramuscularly on muscles closest to the pathologic site on ultrasonography. The IC-BV group received bee venom herbal acupuncture intracuta- neously on LE110, LE201, ST35, ST36 and LR8. Bee venom herbal acupuncture was applied twice a week for 4 weeks by an oriental medical doctor at Kyung-hee Oriental Medical Hospital.
Both groups were checked of pathologic site by ultrasonography before treatment and follow up after four-week treatment. The patients were assessed by KWOMAC and SF-36 before and after four-week treatment. The changes in patients’ pain was measured by VAS before treatment and after one-, two-, three- and four-week treatment. The patients’ overall treatment outcome assesment was measured by Nine Point Scale after four-week treatment.
Results : The results were as follows ;
1. The IM-BV group showed significant improvement on total, pain, stiffness and physical function in KWOMAC, and the IC-BV group showed significant improvement on total and physical function in KWOMAC after 4weeks compared to the pre-treatment. In KWOMAC, the IM-BV group showed more improvement on average compared to the IC-BV group, but there were no significant difference bet- ween two groups.
2. The IM-BV group showed significant improvement on VAS after one-week treatment. The IC-BV group showed significant improvement on VAS after two-week treatment. But there were no significant dif- ference between two groups.
3. The IM-BV group showed significant improvement on physical functioning(PF) and bodily pain(BP) in SF-36, and the IC-BV group showed significant improvement on vitality(VT) and bodily pain(BP) in SF-36 after 4weeks compared to the pre-treatment. But there were no significant difference bet- ween two groups.
4. 88.2% of IM-BV group and 93.3% of IC-BV group graded their improvement as ‘Fair’ or better on Nine Point Scale. But there were no significant difference between two groups.
Conclusions : This study suggests that in the treatment of knee osteoarthtitis patients, effects of ‘In- tramuscular Bee Venom Herbal Acupuncture’ were not different from ‘Intracutaneous Bee Venom Herbal Acupuncture’ statistically. But both treatment showed effects on pain and physical function in knee osteo- arthtitis patients.

영어초록

Objectives : This study was designed to compare the effects on Korean Western Ontario and McMaster Universities Osteoarthritis Index(KWOMAC), 36-Items Short-Form Health Survey(SF-36), Visual Analog Scale(VAS) and Nine Point Scale between ‘Intramuscular Bee Venom Herbal Acupuncture’ and ‘Intracu- taneous Bee Venom Herbal Acupuncture’ in knee osteoarthritis patients for 4weeks.
Methods : All the voluntary subject were diagnosed as knee osteoarthritis. Patients were randomly assigned either to two groups : Intramuscular bee venom herbal acupuncture treatment group(IM-BV group) or Intracutaneous bee venom herbal acupuncture treatment group(IC-BV group).
The IM-BV group received bee venom herbal acupuncture intramuscularly on muscles closest to the pathologic site on ultrasonography. The IC-BV group received bee venom herbal acupuncture intracuta- neously on LE110, LE201, ST35, ST36 and LR8. Bee venom herbal acupuncture was applied twice a week for 4 weeks by an oriental medical doctor at Kyung-hee Oriental Medical Hospital.
Both groups were checked of pathologic site by ultrasonography before treatment and follow up after four-week treatment. The patients were assessed by KWOMAC and SF-36 before and after four-week treatment. The changes in patients’ pain was measured by VAS before treatment and after one-, two-, three- and four-week treatment. The patients’ overall treatment outcome assesment was measured by Nine Point Scale after four-week treatment.
Results : The results were as follows ;
1. The IM-BV group showed significant improvement on total, pain, stiffness and physical function in KWOMAC, and the IC-BV group showed significant improvement on total and physical function in KWOMAC after 4weeks compared to the pre-treatment. In KWOMAC, the IM-BV group showed more improvement on average compared to the IC-BV group, but there were no significant difference bet- ween two groups.
2. The IM-BV group showed significant improvement on VAS after one-week treatment. The IC-BV group showed significant improvement on VAS after two-week treatment. But there were no significant dif- ference between two groups.
3. The IM-BV group showed significant improvement on physical functioning(PF) and bodily pain(BP) in SF-36, and the IC-BV group showed significant improvement on vitality(VT) and bodily pain(BP) in SF-36 after 4weeks compared to the pre-treatment. But there were no significant difference bet- ween two groups.
4. 88.2% of IM-BV group and 93.3% of IC-BV group graded their improvement as ‘Fair’ or better on Nine Point Scale. But there were no significant difference between two groups.
Conclusions : This study suggests that in the treatment of knee osteoarthtitis patients, effects of ‘In- tramuscular Bee Venom Herbal Acupuncture’ were not different from ‘Intracutaneous Bee Venom Herbal Acupuncture’ statistically. But both treatment showed effects on pain and physical function in knee osteo- arthtitis patients.

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