太白⋅神門 捻轉 및 迎隨 補瀉手技法이 2K1C에 의하여 誘發된 腎血管性 高血壓 白鼠에 미치는 影響 (The Effect of Acupuncture by Needle Manipulation at SP3･HT7 on the Blood Pressure in Hypertensive Rats Induced by Two Kidney One Clip (2K1C))

서지정보

· 발행기관 : 경락경혈학회
· 수록지 정보 : Korean Journal of Acupuncture / 28권 / 2호 / 1 ~ 11페이지
· 저자명 : 윤대환, 한정희, 김선희

초록

Objectives : The aim of this study was to examine the effect acupuncture by needle manipulation at acupoints, SP3･HT7, on the blood pressure and renin and atrial natriuretic peptide(ANP) in plasma, cardiac hypertrophy in hypertensive rats induced by two kidney one clip (2K1C).
Materials and Methods : The experiments were performed on twenty-five Sprague Dawley rats, 2K1C hypertension model was prepared by constricting the left renal artery with a sliver clip. Animals were divided into five groups, control, AC-1a and AC-2a(acupuncture at SP3･HT7 bilaterally and the needle was twirled and rotated forward with the thumb and forefinger of the right hand 6 times), AC-3a(acupuncture at SP3･HT7 bilaterally and the needle was inserted in the opposite direction(body direction) as the channel runs), AC-4a(acupuncture at SP3･HT7 bilaterally and the needle was inserted in the opposite direction(body direction) as the channel runs and the needle was twirled and rotated forward with the forefinger of the right hand 6 times). The treatments were started on the 4 week after inducing 2K1C, and they were performed two times a week for 3 weeks in rats.
Results : The results are that The blood pressure was significantly decreased at 4 times in Acu-1a, The cardiac hypertrophy was significantly decrease in Acu-2a and Acu-3a. The activity of plasma renin was decreased in all groups without control and Acu-1a, and that of plasma ANP was decrease in Acu-2a and Acu-3a than control group.
Conclusions : These results suggest that acupuncture on SP3･HT7 mostly cause significant changes on controlling renal hypertension induced by 2K1C in the rats.

영어초록

Objectives : The aim of this study was to examine the effect acupuncture by needle manipulation at acupoints, SP3･HT7, on the blood pressure and renin and atrial natriuretic peptide(ANP) in plasma, cardiac hypertrophy in hypertensive rats induced by two kidney one clip (2K1C).
Materials and Methods : The experiments were performed on twenty-five Sprague Dawley rats, 2K1C hypertension model was prepared by constricting the left renal artery with a sliver clip. Animals were divided into five groups, control, AC-1a and AC-2a(acupuncture at SP3･HT7 bilaterally and the needle was twirled and rotated forward with the thumb and forefinger of the right hand 6 times), AC-3a(acupuncture at SP3･HT7 bilaterally and the needle was inserted in the opposite direction(body direction) as the channel runs), AC-4a(acupuncture at SP3･HT7 bilaterally and the needle was inserted in the opposite direction(body direction) as the channel runs and the needle was twirled and rotated forward with the forefinger of the right hand 6 times). The treatments were started on the 4 week after inducing 2K1C, and they were performed two times a week for 3 weeks in rats.
Results : The results are that The blood pressure was significantly decreased at 4 times in Acu-1a, The cardiac hypertrophy was significantly decrease in Acu-2a and Acu-3a. The activity of plasma renin was decreased in all groups without control and Acu-1a, and that of plasma ANP was decrease in Acu-2a and Acu-3a than control group.
Conclusions : These results suggest that acupuncture on SP3･HT7 mostly cause significant changes on controlling renal hypertension induced by 2K1C in the rats.

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