돌발성 난청 치료에서 고압산소치료의 역할 (The Role of Hyperbaric Oxygen Therapy in the Treatment of Sudden Sensorineural Hearing Loss)

서지정보

· 발행기관 : 대한이비인후과학회
· 수록지 정보 : 대한이비인후-두경부외과학회지 / 67권 / 1호 / 1 ~ 8페이지
· 저자명 : 김화빈, 오세준

초록

Sudden sensorineural hearing loss (SSNHL) is defined as acute hearing loss of >30 dB at threeconsecutive frequencies, with an abrupt onset (within 3 days). In most patients with SSNHL,an exact cause is rarely identified. Diverse etiological theories have been proposed, includingvascular disease, viral infection, autoimmune disease, inner ear hydrops, and genetic factors.
Based on these hypotheses, various treatments have been tried, including corticosteroids (sys-temic and/or intratympanic), antivirals, vasoactive drugs, and hyperbaric oxygen therapy(HBOT), but the evidence remains inconclusive. The 2019 American Academy of Otolaryn-gology-Head and Neck Surgery guideline had suggested that HBOT can be provided as eitherinitial or salvage treatment when combined with steroid therapy. HBOT, a noninvasive treat-ment involving the inhalation of 100% oxygen at a pressure of >1 atmosphere absolute (ATA)is another treatment option as a method to improve oxygen supply after cochlear damage. Al-though the pressure, frequency, and total time of HBOT remain variable among differentstudies, a protocol of 2.0-2.5 ATA and 10-20 sessions in total are commonly used. The treat-ment strategies for SSNHL have been evolving, and recent attempts involved increasing theeffectiveness through various combinations of systemic steroid, intratympanic steroid, andHBOT. In this review, we will review various studies about HBOT and discuss the efficacy of HBOT in SSNHL.

영어초록

Sudden sensorineural hearing loss (SSNHL) is defined as acute hearing loss of >30 dB at threeconsecutive frequencies, with an abrupt onset (within 3 days). In most patients with SSNHL,an exact cause is rarely identified. Diverse etiological theories have been proposed, includingvascular disease, viral infection, autoimmune disease, inner ear hydrops, and genetic factors.
Based on these hypotheses, various treatments have been tried, including corticosteroids (sys-temic and/or intratympanic), antivirals, vasoactive drugs, and hyperbaric oxygen therapy(HBOT), but the evidence remains inconclusive. The 2019 American Academy of Otolaryn-gology-Head and Neck Surgery guideline had suggested that HBOT can be provided as eitherinitial or salvage treatment when combined with steroid therapy. HBOT, a noninvasive treat-ment involving the inhalation of 100% oxygen at a pressure of >1 atmosphere absolute (ATA)is another treatment option as a method to improve oxygen supply after cochlear damage. Al-though the pressure, frequency, and total time of HBOT remain variable among differentstudies, a protocol of 2.0-2.5 ATA and 10-20 sessions in total are commonly used. The treat-ment strategies for SSNHL have been evolving, and recent attempts involved increasing theeffectiveness through various combinations of systemic steroid, intratympanic steroid, andHBOT. In this review, we will review various studies about HBOT and discuss the efficacy of HBOT in SSNHL.

참고자료

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