불화수소산 노출 환자에서 동맥 내 글루콘 산 칼슘 주입 치료 후 조직 손상의 정도와 임상지표 간의 비교 분석 (A Comparative Study of Tissue Injury Grades, with Clinical Factors, in Patients with Hydrofluoric Acid Burns who Received Intra-arterial Infusion of Calcium Gluconate)

서지정보

· 발행기관 : 대한응급의학회
· 수록지 정보 : 대한응급의학회지 / 25권 / 3호 / 252 ~ 260페이지
· 저자명 : 이지한, 인용남, 강준호, 한규홍, 민진홍, 박정수, 김훈, 이석우

초록

Purpose: Hydrofluoric acid (HFA) causes injury via tissuepenetration by the free fluoride ion. Methods for treatmentof HFA burns include continuous intra-arterial infusion ofcalcium gluconate, which is especially useful for patientswith dermal burns of the digits caused by HFA. However,no comparative study of tissue injury grade with clinical factorsamong patients with HFA burns treated with continuousintra-arterial infusion of calcium gluconate has been conductedin Korea.
Methods: We conducted a prospective study at the emergencydepartment of a university teaching hospital betweenJanuary 2011 and June 2013. The subjects enrolled in thisstudy consisted of 33 patients with HFA burns. After completionof treatment, we divided the patients into threegroups according to the type of skin lesions. Patients requiringa skin graft or surgical flap were included in the pooroutcome group, those who had to undergo incision anddrainage in the moderate outcome group, and those whodid not require further treatment in the good outcome group.
Results: After completion of all treatments, 22 of the 33patients were included in the good outcome group andseven in the moderate outcome group; the remaining fourpatients were included in the poor outcome group, as theymet the above-mentioned criteria, experienced longer-lastingpain, and were more frequently treated with injection incomparison with the other patients.
Conclusion: Patients with HFA burns with long-term painwho need frequent arterial injections despite undergoingintra-arterial calcium gluconate treatment are likely to havepoor outcome; therefore, they require more proactive interventions.

영어초록

Purpose: Hydrofluoric acid (HFA) causes injury via tissuepenetration by the free fluoride ion. Methods for treatmentof HFA burns include continuous intra-arterial infusion ofcalcium gluconate, which is especially useful for patientswith dermal burns of the digits caused by HFA. However,no comparative study of tissue injury grade with clinical factorsamong patients with HFA burns treated with continuousintra-arterial infusion of calcium gluconate has been conductedin Korea.
Methods: We conducted a prospective study at the emergencydepartment of a university teaching hospital betweenJanuary 2011 and June 2013. The subjects enrolled in thisstudy consisted of 33 patients with HFA burns. After completionof treatment, we divided the patients into threegroups according to the type of skin lesions. Patients requiringa skin graft or surgical flap were included in the pooroutcome group, those who had to undergo incision anddrainage in the moderate outcome group, and those whodid not require further treatment in the good outcome group.
Results: After completion of all treatments, 22 of the 33patients were included in the good outcome group andseven in the moderate outcome group; the remaining fourpatients were included in the poor outcome group, as theymet the above-mentioned criteria, experienced longer-lastingpain, and were more frequently treated with injection incomparison with the other patients.
Conclusion: Patients with HFA burns with long-term painwho need frequent arterial injections despite undergoingintra-arterial calcium gluconate treatment are likely to havepoor outcome; therefore, they require more proactive interventions.

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