레이저홍채절개술 단독 치료와 아르곤레이저주변홍채성형술 병용 치료 후 전안부빛간섭단층촬영 결과 비교 (Change in Angle Parameters Measured by Anterior Segment Optical Coherence Tomography after Laser Peripheral Iridotomy Alone versus Laser Peripheral Iridotomy and Argon Laser Peripheral Iridoplasty)

서지정보

· 발행기관 : 대한안과학회
· 수록지 정보 : 대한안과학회지 / 52권 / 5호 / 566 ~ 573페이지
· 저자명 : 박형주, 박기호, 김석환, 김태우, 김동명

초록

목적: 원발폐쇄각 환자에서 레이저홍채절개술 단독치료와 레이저홍채절개술과 아르곤레이저 주변홍채성형술 병용치료 후 전안부 구 조의 변화를 전안부 빛간섭단층촬영을 통해 비교 분석하고자 하였다. 대상과 방법: 본원 안과에서 원발폐쇄각 또는 원발폐쇄각녹내장으로 진단받은 환자 17명 25안을 대상으로 11안에서 레이저홍채절개술 단독치료(단독군), 14안에서 레이저홍채절개술과 아르곤레이저 주변홍채성형술 병용치료(병용군)를 시행하였다. 전안부 빛간섭단층촬 영으로 시술 전후 anterior chamber depth (ACD), angle opening distance at 500 μm and 750 μm (AOD 500 and AOD 750), angle recess area at 500 μm and 750 μm (ARA 500 and ARA 750), trabecular-iris space area at 500 μm and 750 μm (TISA 500 and TISA 750), trabecular-iris angle (TIA)를 비교하였다. 결과: 두 군 모두 시술 전보다 시술 후 AOD 500, AOD 750, ARA 500, ARA 750, TISA 500, TISA 750, TIA는 유의하게 증가하였다(LPI treatment group: p=0.003, p=0.006, p=0.013; LPI and ALPI combined treatment group: p=0.001, p=0.001, p=0.001). 단독군보다 병용군에서 시술 전후의 AOD 500 차이, TISA 500 차이, 그리고 TISA 750 차이가 유의하게 증가하였다(p=0.112, p=0.147, p=0.049, p=0.037). 결론: 레이저홍채절개술 단독치료와 레이저홍채절개술과 아르곤레이저주변홍채성형술 병용치료 모두 전방각을 유의하게 넓혔으며 병 용군에서 더 큰 효과를 보였다.

영어초록

Purpose: To compare the changes in angle parameters after laser peripheral iridotomy (LPI) alone versus LPI and ALPI (argon laser peripheral iridoplasty) in primary angle closure patients by using anterior segment optical coherence tomography (AS-OCT). Methods: A total of 25 eyes from 17 patients with narrow angles were enrolled in this present study. Eleven eyes in the LPI treatment group and 14 eyes in the LPI and ALPI combined treatment group were evaluated using AS-OCT. The anterior chamber depth (ACD), angle opening distance at 500 μm (AOD 500) and 750 μm (AOD 750), angle recess area at 500 μm (ARA 500) and 750 μm (ARA 750), trabecular-iris space area at 500 μm (TISA 500) and 750 μm (TISA 750), trabecular-iris angle (TIA) were measured. The pre- and post-treatment parameters were compared in each group. The parameter changes after laser treatment were also compared. Results: AOD 500, AOD 750, ARA 500, ARA 750, TISA 500 and TISA 750 except ACD significantly increased following LPI treatment (p = 0.013, p = 0.010, p = 0.008, p = 0.003, p = 0.006, p = 0.003, p = 0.013, respectively, Wilcoxon signed rank test) and LPI and ALPI combined therapy (p = 0.001, p = 0.001, p = 0.001, p = 0.001, p = 0.001, p = 0.001, p = 0.001, respectively, Wilcoxon signed rank test). The AOD 500 difference, TISA 500 difference, and TISA 750 difference were significantly greater after LPI and ALPI combined therapy than after LPI treatment alone (p = 0.112, p = 0.147, p = 0.049, p = 0.037, respectively, Mann-Whitney U-test). Conclusions: The results from the present study showed LPI alone or LPI and ALPI combined therapy significantly widened the anterior chamber angle and combined therapy showed greater effect than LPI alone.

참고자료

· 없음