조현병 환자에서 성별에 따른 인지기능의 차이 (Gender Differences in Cognitive Function of Schizophrenia Patients)

서지정보

· 발행기관 : 대한조현병학회
· 수록지 정보 : 대한조현병학회지 / 27권 / 2호 / 72 ~ 77페이지
· 저자명 : 박경환, 최말례, 신예은, 한명일

초록

Objectives: Cognitive impairment is a fundamental symptom of schizophrenia, an often-overlooked aspect of the disorder that has gained recent attention due to its direct relation with functional outcomes and implications for medical and social costs. This study aims to investigate gender differences in cognitive function among patients with schizophrenia using Korean Wechsler Adult Intelligence Scale-IV (K-WAIS-IV).


Methods: Data were collected from inpatients and outpatients treated at Presbyterian Medical Center between January 1, 2019, and December 31, 2023. Patients diagnosed with schizophrenia underwent evaluation with the K-WAIS-IV. Multivariate analysis of variance was utilized to assess cognitive differences between men and women participants, while correlation analysis was performed to explore associations between cognitive performance and clinical data.


Results: Among 101 candidates, 26 male and 26 female patients were selected for analysis of their K-WAIS-IV scores and clinical data.
The results revealed no statistically significant differences in cognitive function between male and female patients concerning Full-Scale Intelligence Quotient (FSIQ) and the four index scores: Verbal Comprehension Index (VCI), Perceptual Reasoning Index (PRI), Working Memory Index (WMI), and Processing Speed Index (PSI). A trend indicating preserved verbal intelligence relative to performance intelligence was observed. Additionally, the VCI exhibited a positive correlation with age, while both FSIQ and PSI demonstrated positive correlations with years of education.


Conclusion: The findings of this investigation suggest that there are no significant differences in cognitive function between male and female patients with schizophrenia via K-WAIS-IV. Given the heterogeneity of the sample and potential limitations of the neurocognitive assessments employed, further research utilizing more targeted methodologies and sensitive measures is warranted.

영어초록

Objectives: Cognitive impairment is a fundamental symptom of schizophrenia, an often-overlooked aspect of the disorder that has gained recent attention due to its direct relation with functional outcomes and implications for medical and social costs. This study aims to investigate gender differences in cognitive function among patients with schizophrenia using Korean Wechsler Adult Intelligence Scale-IV (K-WAIS-IV).


Methods: Data were collected from inpatients and outpatients treated at Presbyterian Medical Center between January 1, 2019, and December 31, 2023. Patients diagnosed with schizophrenia underwent evaluation with the K-WAIS-IV. Multivariate analysis of variance was utilized to assess cognitive differences between men and women participants, while correlation analysis was performed to explore associations between cognitive performance and clinical data.


Results: Among 101 candidates, 26 male and 26 female patients were selected for analysis of their K-WAIS-IV scores and clinical data.
The results revealed no statistically significant differences in cognitive function between male and female patients concerning Full-Scale Intelligence Quotient (FSIQ) and the four index scores: Verbal Comprehension Index (VCI), Perceptual Reasoning Index (PRI), Working Memory Index (WMI), and Processing Speed Index (PSI). A trend indicating preserved verbal intelligence relative to performance intelligence was observed. Additionally, the VCI exhibited a positive correlation with age, while both FSIQ and PSI demonstrated positive correlations with years of education.


Conclusion: The findings of this investigation suggest that there are no significant differences in cognitive function between male and female patients with schizophrenia via K-WAIS-IV. Given the heterogeneity of the sample and potential limitations of the neurocognitive assessments employed, further research utilizing more targeted methodologies and sensitive measures is warranted.

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