봉독을 이용한 무작위배정 임상연구의 국내 현황 (The Review on the Randomized Controlled Clinical Trials of Bee Venom in the Journal of Korean Medicine)

서지정보

· 발행기관 : 한방재활의학과학회
· 수록지 정보 : 한방재활의학과학회지 / 23권 / 3호 / 87 ~ 106페이지
· 저자명 : 이용석, 이영준, 한창현

초록

Objectives We will provide basic information on bee venom clinical tests and aid thepractical use of bee venom in such tests, through examination of RCT research related tobee venom that was reported domestically.
Methods We collected 365 articles on Bee venom study result from the OASIS systemusing the Keyword ‘bee venom, apitoxin, apitherapy, bee sting’. The initially selected theseswere primarily screened for clinical research. Out of these, case studies and nonrandomized controlled trial (non-RCT) were ruled out. As a result, 39 studies of randomizedcontrolled trial (RCT) research were chosen as the subjects of study.
Results RCT research related to bee venom was first presented in 2003, and 39 studieshave been published until 2012. 18 studies were tests to confirm the effectiveness of beevenom, 7 studies were comparisons between SBV and BV, and 13 studies were comparisonswith other types of treatment. Research conducted through appropriate randomizationmethods were 20 studies, and inappropriate randomization methods were used in19 studies. In therms of Jadad score, 12 studies received 4~5 points, 15 studies received1~3 points, and 12 studies received zero point.
Conclusions In order to assure good quality RCT research, appropriate guidelinesshould be provided, and proper evaluation standards should be established. In-depthstudy is needed concerning the difference of responses to treatment according to thetypes of treatment received. A standardization of treatment should be reached as a result.

영어초록

Objectives We will provide basic information on bee venom clinical tests and aid thepractical use of bee venom in such tests, through examination of RCT research related tobee venom that was reported domestically.
Methods We collected 365 articles on Bee venom study result from the OASIS systemusing the Keyword ‘bee venom, apitoxin, apitherapy, bee sting’. The initially selected theseswere primarily screened for clinical research. Out of these, case studies and nonrandomized controlled trial (non-RCT) were ruled out. As a result, 39 studies of randomizedcontrolled trial (RCT) research were chosen as the subjects of study.
Results RCT research related to bee venom was first presented in 2003, and 39 studieshave been published until 2012. 18 studies were tests to confirm the effectiveness of beevenom, 7 studies were comparisons between SBV and BV, and 13 studies were comparisonswith other types of treatment. Research conducted through appropriate randomizationmethods were 20 studies, and inappropriate randomization methods were used in19 studies. In therms of Jadad score, 12 studies received 4~5 points, 15 studies received1~3 points, and 12 studies received zero point.
Conclusions In order to assure good quality RCT research, appropriate guidelinesshould be provided, and proper evaluation standards should be established. In-depthstudy is needed concerning the difference of responses to treatment according to thetypes of treatment received. A standardization of treatment should be reached as a result.

참고자료

· 없음