일 대학병원 정신건강의학과 입원 환자에서 비타민D 결핍의 발생률과 우울증상, 인지기능의 연관성 (The Relationships among Vitamin D Deficiency, Depressive Symptoms, and Cognitive Functions in the Psychiatric Inpatients of a University Hospital)

서지정보

· 발행기관 : 대한우울조울병학회
· 수록지 정보 : Mood and Emotion / 15권 / 3호 / 138 ~ 143페이지
· 저자명 : 김미영, 박종일, 양종철, 박태원, 정영철, 정상근

초록

Objectives : To investigate the relationship between the degree of vitamin D deficiency and psychiatric symptoms among psychiatric inpatients. Studies on the association of vitamin D status with mental illnesses have been reported.
However, the relationship of hypovitaminosis D with measures of depressive symptoms and cognitive functions remains unclear. Methods : A sample of 108 psychiatric inpatients were enrolled with a manner of a retrospective study. Using serum levels of 25-hydroxyvitamin D [25(OH)D] and scores on the BDI and MMSE, an association between vitamin D level and depressive symptoms/cognitive declines were evaluated with Fisher’s exact tests and Pearson’s correlation analysis. Results : Sixty-seven patients (62%) were classified as deficient in vitamin D. Serum 25(OH)D concentrations did not reveal significant difference between the groups. Additionally, there was no significant correlation between serum 25-OH vitamin D level and depressive symptoms and cognitive functions. Conclusion : Vitamin D deficiency is common among psychiatric patients, independent of diagnostic category. Even though the role of vitamin D in psychiatric disorders is unclear, concerns about vitamin D deficiency and psychiatric approaches are necessary. Future studies on the relationship between vitamin D deficiency and major psychiatric symptoms are needed.

영어초록

Objectives : To investigate the relationship between the degree of vitamin D deficiency and psychiatric symptoms among psychiatric inpatients. Studies on the association of vitamin D status with mental illnesses have been reported.
However, the relationship of hypovitaminosis D with measures of depressive symptoms and cognitive functions remains unclear. Methods : A sample of 108 psychiatric inpatients were enrolled with a manner of a retrospective study. Using serum levels of 25-hydroxyvitamin D [25(OH)D] and scores on the BDI and MMSE, an association between vitamin D level and depressive symptoms/cognitive declines were evaluated with Fisher’s exact tests and Pearson’s correlation analysis. Results : Sixty-seven patients (62%) were classified as deficient in vitamin D. Serum 25(OH)D concentrations did not reveal significant difference between the groups. Additionally, there was no significant correlation between serum 25-OH vitamin D level and depressive symptoms and cognitive functions. Conclusion : Vitamin D deficiency is common among psychiatric patients, independent of diagnostic category. Even though the role of vitamin D in psychiatric disorders is unclear, concerns about vitamin D deficiency and psychiatric approaches are necessary. Future studies on the relationship between vitamin D deficiency and major psychiatric symptoms are needed.

참고자료

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