췌장 낭성 종괴로 발현한 인슐린종 1예 (Cystic Insulinoma of the Pancreas)

서지정보

· 발행기관 : 대한내분비학회
· 수록지 정보 : Endocrinology and Metabolism / 21권 / 6호 / 552 ~ 555페이지
· 저자명 : 조선욱, 이은정, 곽수헌, 조영민, 신찬수, 박경수, 김성연, 조보연, 이홍규

초록

췌장의 낭성 내분비 종양은 임상적으로 매운 드문 질환으로, 모든 췌장 내분비 종양의 2~3%에 불과하다. 저자들은 췌장의 낭성 인슐린 종양으로 진단 받고 수술로써 완치된 우리나라 첫 증례를 보고하며, 췌장의 낭성 종양의 한 감별 진단으로 췌장 내분비 질환, 특히 인슐린종이 포함되어야 함을 강조하고자 한다.

영어초록

Cystic islet cell neoplasms are among the rarest entities in the differential diagnosis of cystic tumor of the pancreas, and this malady raises difficult clinical problems. The diagnosis of insulinoma could be difficult if the functional activity is incomplete, which possibly leads to blunted symptoms of hypoglycemia and failure in the laboratory to provide evidence of hyperinsulinemia. Furthermore, if the imaging shows a smaller tumor than usual or an unusual morphology like cyctic tumor, then physicians can become somewhat confused. We report here on a clinical case of cystic insulinoma with the typical neuroglycopenic symptoms and laboratory- confirmed hyperinsulinemia. At resection, a 2-cm cavitary mass without central necrosis was excised and this was confirmed histologically as a purely cystic insulioma. This is the first report of a functional cystic insulinoma of the pancreas in Korea. We suggest that the differential diagnosis of endocrine tumor must be considered for any pancreatic cyst, and especially when it is discovered in a patient who is clinically suggestive of having the associated syndrome. (J Kor Endocrinol Soc 21:552~555, 2006)

참고자료

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