자가면역성 간염과 동반된 전신성 홍반성 낭창 및 원발성 쇼그렌 증후군 (Two Cases of Autoimmune Hepatitis Accompanied by Connective Tissue Diseases)

서지정보

· 발행기관 : 대한내과학회
· 수록지 정보 : 대한내과학회지 / 80권 / 6호 / 697 ~ 702페이지
· 저자명 : 이규진, 최정민, 한병훈, 이상욱, 윤병철, 김근태, 허방

초록

저자들은 황달 및 가려움증을 호소하는 52세 여자와 60세 여자에서 각각 자가면역성 간염과 동반된 전신성 홍반성 낭창과 원발성 쇼그렌 증후군을 경험하여 문헌고찰과 함께 보고하고자 한다.

영어초록

Autoimmune hepatitis is a generally progressive chronic hepatitis of unknown etiology. Systemic lupus erythematosus (SLE) and Sjögren’s syndrome are chronic, multifaceted inflammatory diseases that can affect every organ system, although hepatic involvement is rare. Here, we report two rare cases: autoimmune hepatitis associated with SLE and with primary Sjögren's syndrome. A 52-year-old woman and a 60-year-old woman were admitted our hospital with jaundice and pruritus. They had no history of viral hepatitis, alcohol consumption, or drug use. The pathological findings, clinical manifestations, and laboratory findings satisfied each of the diagnostic criteria for autoimmune hepatitis as well as for SLE and Sjögren’s syndrome in the first and second cases, respectively. These patients were treated with prednisolone, and then followed regularly. (Korean J Med 2011;80:697-702)

참고자료

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