운동부하검사 시 혈압 및 심박수의 상승과 좌심방 용적지수 및 맥파전달속도의 연관성 (Association of Blood Pressure and Heart Rate Response to Graded Exercise Test with Left Atrial Volume Index and Pulse Wave Velocity)

서지정보

· 발행기관 : 대한고혈압학회
· 수록지 정보 : Clinical Hypertension / 19권 / 2호 / 45 ~ 54페이지
· 저자명 : 박재호, 진선아, 이영달, 성석우, 이현석, 김미주, 박광인, 오진경, 박수진, 안계택, 김준형, 박재형, 이재환, 최시완, 성인환, 정진옥

초록

Background: Exaggerated blood pressure (BP) response to exercise can be an independent risk factor for cardiovascular mortality and morbidity. The purpose of this study was to define the factor that effect on early systolic BP response to exercise. Methods: We examined echocardiographic data, BP, heart rate from graded exercise test and brachial ankle pulse wave velocity (PWV) of 205 patients (137 men and 68 women; mean age 58 ± 11 years; range, 19 to 83 years). Graded exercise test was conducted in BRUCE protocol. We define delta systolic blood pressure (SBP) as systolic BRUCE stage “n” BP minus baseline BP. Results: Resting BP (127 ± 16 mm Hg) was elevated to 171 ± 26 mm Hg after peak graded exercise test. Resting heart rate (80 ± 15 bpm) was increased to 146 ± 27 bpm after peak graded exercise test. Stepwise regression test between baseline SBP, delta SBP, maximal SBP and left atrial volume index (LAVI) was done. Supine SBP,delta SBP, maximal SBP was not associated with LAVI (p > 0.5). But increased LAVI was significantly associated with delta SBP1 in woman (R2 = 0.192, p = 0.002). PWV was significantly associated with base line (R2 = 0.311, p < 0.01) and maximal SBP (R2 = 0.051, p < 0.01). However, PWV was not associated with delta SBP. Conclusions: LAVI and PWV were not associated with early SBP response to exercise. But in women, elevation of early SBP during exercise is associated with LAVI.

영어초록

Background: Exaggerated blood pressure (BP) response to exercise can be an independent risk factor for cardiovascular mortality and morbidity. The purpose of this study was to define the factor that effect on early systolic BP response to exercise. Methods: We examined echocardiographic data, BP, heart rate from graded exercise test and brachial ankle pulse wave velocity (PWV) of 205 patients (137 men and 68 women; mean age 58 ± 11 years; range, 19 to 83 years). Graded exercise test was conducted in BRUCE protocol. We define delta systolic blood pressure (SBP) as systolic BRUCE stage “n” BP minus baseline BP. Results: Resting BP (127 ± 16 mm Hg) was elevated to 171 ± 26 mm Hg after peak graded exercise test. Resting heart rate (80 ± 15 bpm) was increased to 146 ± 27 bpm after peak graded exercise test. Stepwise regression test between baseline SBP, delta SBP, maximal SBP and left atrial volume index (LAVI) was done. Supine SBP,delta SBP, maximal SBP was not associated with LAVI (p > 0.5). But increased LAVI was significantly associated with delta SBP1 in woman (R2 = 0.192, p = 0.002). PWV was significantly associated with base line (R2 = 0.311, p < 0.01) and maximal SBP (R2 = 0.051, p < 0.01). However, PWV was not associated with delta SBP. Conclusions: LAVI and PWV were not associated with early SBP response to exercise. But in women, elevation of early SBP during exercise is associated with LAVI.

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