뇌졸중 환자와 정상인의 근 수축 유형에 따른 피질 신경원의 활성도 비교 (Comparison of the Activity of Cortical Neurons According to Muscle Contraction Type between Post Stroke Hemiplegic Subjects and Healthy Subjects)

서지정보

· 발행기관 : 대한물리치료학회
· 수록지 정보 : 대한물리치료학회지 / 21권 / 1호 / 73 ~ 80페이지
· 저자명 : 양가애, 김태열, 김수현, 임영은, 이동걸

초록

Purpose: In order to examine difference in the activity of potential of spinal neurons and cortical neurons according
to muscle contraction type in post stroke hemiplegic subjects and healthy subjects, the present study conducted an
experiment as follows.
Methods: The subjects in the experimental group were 17 left‐side hemiplegic subjects (9 female, 8 male; mean age,
63.41±9.86 years) with the right hand as the dominant hand selected among post stroke hemiplegic subjects, and 17 age
matched healthy control subjects (10 female, 7 male; mean age, 64.12±12.07 years). Movement‐related cortical potentials
(MRCPs) were measured using surface electromyography and electroencephalography while concentric and eccentric
movements were made alternately.
Results: As to the pattern of the activity of MRCP, which indicates the activity of motor cortical neurons, we found
that the amplitude is high (p<0.01), the length of excitement is short (p<0.01) and the ascending gradient of amplitude
to the peak increases (p<0.05) in post stroke hemiplegic subjects’ lesion sites different from healthy subjects.
Conclusion: The activity of cortical neurons was no difference in activity according to contraction type was observed
in post stroke hemiplegic subjects’ lesion sites. This suggests that there is no distinction in the activity of cortical
neurons between concentric contraction and eccentric contraction. Accordingly, if post stroke hemiplegic subjects’
activity of motor cortex is analyzed by measuring MRCPs, it is considered useful in research on neural plasticity or as
a ground of clinical effects in the area of physical therapy for the central nervous system.

영어초록

Purpose: In order to examine difference in the activity of potential of spinal neurons and cortical neurons according
to muscle contraction type in post stroke hemiplegic subjects and healthy subjects, the present study conducted an
experiment as follows.
Methods: The subjects in the experimental group were 17 left‐side hemiplegic subjects (9 female, 8 male; mean age,
63.41±9.86 years) with the right hand as the dominant hand selected among post stroke hemiplegic subjects, and 17 age
matched healthy control subjects (10 female, 7 male; mean age, 64.12±12.07 years). Movement‐related cortical potentials
(MRCPs) were measured using surface electromyography and electroencephalography while concentric and eccentric
movements were made alternately.
Results: As to the pattern of the activity of MRCP, which indicates the activity of motor cortical neurons, we found
that the amplitude is high (p<0.01), the length of excitement is short (p<0.01) and the ascending gradient of amplitude
to the peak increases (p<0.05) in post stroke hemiplegic subjects’ lesion sites different from healthy subjects.
Conclusion: The activity of cortical neurons was no difference in activity according to contraction type was observed
in post stroke hemiplegic subjects’ lesion sites. This suggests that there is no distinction in the activity of cortical
neurons between concentric contraction and eccentric contraction. Accordingly, if post stroke hemiplegic subjects’
activity of motor cortex is analyzed by measuring MRCPs, it is considered useful in research on neural plasticity or as
a ground of clinical effects in the area of physical therapy for the central nervous system.

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