시야결손전녹내장환자에서 표준자동시야검사의 토탈데비에이션과 주파수배가시야검사의 비교 (Comparison of Total Deviation of Standard Automated Perimetry and Matrix FDT in Preperimetric Glaucoma Patients)

서지정보

· 발행기관 : 대한안과학회
· 수록지 정보 : 대한안과학회지 / 51권 / 2호 / 220 ~ 226페이지
· 저자명 : 최정훈, 박인원, 정윤석

초록

목적: 시야결손전녹내장환자에서 표준자동시야검사와 Matrix 주파수배가시야검사를 비교하여 표준자동시야검사 total deviation (TD)의 임상적 의미를 알아보고자 하였다.
대상과 방법: 시야결손전녹내장환자 52명 52안을 대상으로 Matrix 주파수배가시야검사와 빛간섭단층촬영(Optical coherence tomography;OCT)를 시행하였다. 표준자동시야검사 TD, Matrix TD와 pattern deviation (PD)의 비정상율을 구하고 연관성을 알아보았으며, 또한OCT 결과와의 상관관계를 분석하였다.
결과: 표준자동시야검사 TD 22안(42.3%), Matrix TD 34안(65.4%) 및 PD 41안(78.9%)이 비정상을 보였으며 표준자동시야검사 TD와Matrix PD 간에는 경계적 유의성을 보였다(p=0.07). 또한 Matrix PD와 OCT 간에는 유의한 상관관계가 있었다(p＜0.05). 그러나 표준자동시야검사 TD와 OCT 간에는 유의한 상관관계를 보이지 않았지만 Matrix PD 비정상 환자 중에서 표준자동시야검사 TD가 비정상인경우가 정상에 비해 평균, 12시, 5시, 상측 사분역에서 유의한 망막신경섬유층의 두께 감소를 보여주었다(p＜0.05).
결론: 시야결손전녹내장환자에서 표준자동시야검사의 TD결과는 42.3%의 비정상율을 보여주었으며 이는 환자의 임상적 평가에 유용하게 사용될 수 있을 것으로 생각된다.

영어초록

Purpose: To compare the results of total deviation (TD) as measured by standard automated perimetry (SAP) and measured with of Matrix Frequency-doubling Technology (FDT) in patients with preperimetric glaucoma.
Methods: Fifty-two eyes of 52 patients with preperimetric glaucoma were included. Subjects were examined with Matrix FDT and Stratus optical coherence tomography (OCT), and the results of each examination were analyzed. The proportions of abnormal results in SAP TD, Matrix TD, and Matrix pattern deviation (PD) were calculated. Among the results of tests, the following correlations were evaluated: SAP TD and Matrix, and visual fields and OCT. In addition, the differences in peripapillary retinal nerve fiber layer thickness (RNFL) according to the result of SAP TD in preperimetric patients with abnormal Matrix PD were analyzed.
Results: A abnormalities in SAP TD, Matrix TD and Matrix PD were found in 22 (42.3%), 34 (65.4%), 41 (78.9%) eyes, respectively.
There was marginal correlation between SAP TD and Matrix PD (p=0.07). No significant correlation was found between SAP TD and OCT, although Matrix PD and OCT did show significant correlation (p<0.05). In preperimetric patients with abnormal Matrix PD,RNFL thickness was significantly lower in the abnormal SAP TD group than in the normal SAP TD group on average, in the superior quadrant, and at the 12 o’clock and 5 o’clock positions (p＜0.05).
Conclusions: In patients with preperimetric glaucoma, 42.3% and 78.9% had glaucomatous VF defects in SAP TD and Matrix PD, respectively. These results were higher than expected, especially those of SAP TD.

참고자료

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