칼슘포스페이트 나노-크리스탈이 코팅된 골이식재와 자가하악지골을 병행 이용한 상악동 거상술 (SINUS FLOOR GRAFTING USING CALCIUM PHOSPHATE NANO-CRYSTAL COATED XENOGENIC BONE AND AUTOLOGOUS BONE)

서지정보

· 발행기관 : 대한악안면성형재건외과학회
· 수록지 정보 : Maxillofacial Plastic Reconstructive Surgery / 31권 / 3호 / 243 ~ 248페이지
· 저자명 : 방강미, 이보한, 알라쉬단, 유상배, 성미애, 김성민, 장정원, 김명진, 고재승, 이종호

초록

Purpose: Rehabilitation of the edentulous posterior maxilla with dental implants often poses difficulty
because of insufficient bone volume caused by pneumatization of the maxillary sinus and by crestal bone
resorption. Sinus grafting technique was developed to increase the vertical height to overcome this problem.
The present study was designed to evaluate the sinus floor augmentation with anorganic bovine bone (Biocera
TM) using histomorphometric and clinical measures.
Patients and methods: Thirteen patients were involved in this study and underwent total 14 sinus lift
procedures. Residual bone height was ≥2mm and ≤6mm. Lateral window approach was used, with grafting
using Bio-cera™ only(n=1) or mixed with autogenous bone from ramus and/or maxillary
tuberosity(n=13). After 6 months of healing, implant sites were created with 3mm diameter trephine and
biopsies taken for histomorphometric analysis. The parameters assessed were area fraction of new bone,
graft material and connective tissue. Immediate and 6 months after grafting surgery, and 6 months after
implantation, computed tomography (CT) was taken and the sinus graft was evaluated morphometric
analysis. After implant installation at the grafted area, the clinical outcome was checked.
Results: Histomorphometry was done in ten patients. Bio-cera™ particles were surrounded by newly
formed bone. The graft particles and newly formed bone were surrounded by connective tissue including
small capillaries in some fields. Imaging processing revealed 24.86±7.59% of new bone, 38.20±13.19%
connective tissue, and 36.92±14.51% of remaining Bio-cera™ particles. All grafted sites received an
implant, and in all cases sufficient bone height was achieved to install implants. The increase in ridge
height was about 15.9±1.8mm immediately after operation (from 13mm to 19mm). After 6 months operation,
ridge height was reduced about 11.5±13.5%. After implant installation, average marginal bone loss
after 6 months was 0.3±0.15mm.
Conclusion: Bio-cera™ showed new bone formation similar with Bio-Oss histomorphometrically and
appeared to be an effective bone substitute in maxillary sinus augmentation procedure with the residual
bone height from 2 to 6mm.

영어초록

Purpose: Rehabilitation of the edentulous posterior maxilla with dental implants often poses difficulty
because of insufficient bone volume caused by pneumatization of the maxillary sinus and by crestal bone
resorption. Sinus grafting technique was developed to increase the vertical height to overcome this problem.
The present study was designed to evaluate the sinus floor augmentation with anorganic bovine bone (Biocera
TM) using histomorphometric and clinical measures.
Patients and methods: Thirteen patients were involved in this study and underwent total 14 sinus lift
procedures. Residual bone height was ≥2mm and ≤6mm. Lateral window approach was used, with grafting
using Bio-cera™ only(n=1) or mixed with autogenous bone from ramus and/or maxillary
tuberosity(n=13). After 6 months of healing, implant sites were created with 3mm diameter trephine and
biopsies taken for histomorphometric analysis. The parameters assessed were area fraction of new bone,
graft material and connective tissue. Immediate and 6 months after grafting surgery, and 6 months after
implantation, computed tomography (CT) was taken and the sinus graft was evaluated morphometric
analysis. After implant installation at the grafted area, the clinical outcome was checked.
Results: Histomorphometry was done in ten patients. Bio-cera™ particles were surrounded by newly
formed bone. The graft particles and newly formed bone were surrounded by connective tissue including
small capillaries in some fields. Imaging processing revealed 24.86±7.59% of new bone, 38.20±13.19%
connective tissue, and 36.92±14.51% of remaining Bio-cera™ particles. All grafted sites received an
implant, and in all cases sufficient bone height was achieved to install implants. The increase in ridge
height was about 15.9±1.8mm immediately after operation (from 13mm to 19mm). After 6 months operation,
ridge height was reduced about 11.5±13.5%. After implant installation, average marginal bone loss
after 6 months was 0.3±0.15mm.
Conclusion: Bio-cera™ showed new bone formation similar with Bio-Oss histomorphometrically and
appeared to be an effective bone substitute in maxillary sinus augmentation procedure with the residual
bone height from 2 to 6mm.

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