정량적 전산화 단층촬영법을 이용한 척추 골밀도 측정 (A Study on Spinal Bone Mineral Density Measured with Quantitative Computed Tomography)

서지정보

· 발행기관 : 한국방사선학회
· 수록지 정보 : 한국방사선학회논문지 / 4권 / 2호 / 5 ~ 11페이지
· 저자명 : 여진동, 고인호

초록

골다공성 폐경 후 여성에서 단일 에너지를 이용한 정량적 전산화 단층촬영술로 골무기질 함량을 측정하여 건강한 여성과 비교분석하였다.1군은 건강한 폐경전 여성, 2군은 폐경후 건강한 여성, 3군은 골다공증성 폐경후 여성으로 나눈 환자들에게 QCT를 이용하여 측정된 골밀도가 각 군간에 차이가 있는지 알아보고 각 군내 혹은 다른 군간에 척추 부위에 따른 영향이 있는지를 부위별로 비교분석하였고, 골무기질 함량의 측정은 타원형의 region of interest를 이용하여 T12-L4에서 척추의 해면질 부위에서 측정하였다.


연령이 증가함에 따라 골밀도는 감소하였고 건강한 군과 비교하여 골다공증 환자군에서 유의하게 낮은 골밀도를 관찰 할 수 있었다. 건강한 폐경전 여성군을 제외한 모든군에서 T12에서L4로 갈수록 골밀도가 감소하였다. 통계학적으로 모든 척추체에서 골밀도로 1, 2, 3군간 서로를 구분할 수 있으나 2군과 3군은 골밀도로는 서로간의 구분할 수 없는 것으로 분석되었다.

영어초록

The purpose of this study is to compare and analyze the bone mineral content of women who went through osteoporotic menopause and that of women who are healthy. For the purpose, this researcher sampled some women and divided them into three groups. Group 1 consisted of women who were pre-menopausal and healthy, group 2, women who were post-menopausal and health and group 3, women who went through osteoporotic menopause. The researcher measured the bone density of all the subjects and compared its difference among the three groups. Then the researcher compared and analyzed the influences of bone density on the spine among women of each group or those of all the groups. Among all regions of the spine, that of most region was spongiosa which was ovally shaped. The researcher measured the bone mineral content of spongiosa which existed in a particular section of the spine between T12 and L4. Findings of the study can be summarized as follows.


The older women were, the lower their bone density was. Especially, women who had osteoporosis were significantly lower in bone density than those who were healthy. In all women, except those of group 1, bone density more and more lowered as the measured region of the spine gradually moved from T12 to L4. From a statistical view, the bone density of the entire vertebral body could discriminate the groups 1, 2 and 3. But it was not possible to discriminate between the groups 2 and 3 only with the bone density of the most interested region as mentioned above.

참고자료

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