Does the ADC Map have Additional Clinical Significance Compared to the DWI in the Brain Infarction?

서지정보

· 발행기관 : 대한자기공명의과학회
· 수록지 정보 : Investigative Magnetic Resonance Imaging / 17권 / 4호 / 267 ~ 274페이지
· 저자명 : 최순섭, 하동호, 강명진, 이진화, 윤성국

초록

Purpose : To re-evaluate additional clinical significance of the apparent diffusion coefficient (ADC) map in the inference of infarction stage, authors studied the evolution patterns of the DWI and the ADC map of the brain infarction.
Materials and Methods: In 127 patients with cerebral infarctions, including follow-up checks, 199 studies were performed.
They were classified as hourly (117 studies)-, daily (108 studies)-, weekly (62 studies)-based groups. The signal intensity (SI) was measured at the core of the infarction and contralateral area with ROI of 0.3 cm2 or more on the images of the DWI and the ADC map, and calculated the ratios of SI and ADC value of the infarction area / contralateral normal area, and compared the patterns of the change according to the evolution.
Results: Infarction was detected as early as 1 hour after the attack, and the ratio of SI in the DWI became over than 2after 12 hours, which showed a plateau until the 6th day. Thereafter, it decreased slowly to 1 on the 30th day, and changed to lower SI than the surrounding brain. The ratio in the ADC map became 0.46 in 24 hours after the attack, and increased slowly to 1 in the 15th day. Thereafter, it became a higher value than the surrounding brain. Overall, the ratio in the ADC map changed earlier than in the DWI, and the ratio curves showed inverse pattern each other according to the evolution of the infarction.
Conclusion: The evolution patterns of infarction on the ADC map showed an inverse curve of DWI curve, which means that the ADC value is accurately predictable from DWI, and the ADC map joined with the DWI seems helpful in the determination of subacute infarction between 15 to 30 days.

참고자료

· 없음