청소년기 비만지표와 초기 성인기 경동맥 내중막 두께와의 관련성: Kangwha Study (The association between obesity indices in adolescence and carotid intima-media thickness in young adults: Kangwha Study)

서지정보

· 발행기관 : 대한예방의학회
· 수록지 정보 : 예방의학회지 / 41권 / 2호 / 107 ~ 114페이지
· 저자명 : 이유정, 남정모, 김현창, 허남욱, 서일

초록

Objectives : The aim of this study is to investigate the
association between obesity indices (body mass index,
weight, waist-hip ratio and waist circumference) in
adolescents and the carotid intima-media thickness (C-IMT)
in early adulthood. We also wanted to identify the best
predictor for C-IMT among these obesity indices.
Methods : This study used community-based prospective
cohort study, known as the Kangwha Study, and the data
we used were from subjects who were 16-years old in 1996
(defined as HadolescenceI) and 25 years-old in 2005
(defined as Hearly adulthoodI). The 256 subjects (113 men
and 143 women) who were used for analysis participated in
both follow-ups, and they underwent B-mode
ultrasonography of the carotid arteries at the early
adulthood follow-up. Obesity indices were defined as the
body mass index, weight, waist-hip ratio and waist
circumference. The C-IMT was defined as the mean of the
maximal IMT of each common carotid artery. The C-IMT
and obesity indices associations were evaluated via
multivariable regression, logistic regression and the
receiver-operator characteristic curve analyses.
Results : In men, all the obesity indices in adolescence
were showed to have statistically significant positive
association with C-IMT in early adulthood. However, no
such relationship was showed in women. On multiple
regression and logistic regression analysis, the waist-hip
ratio showed the biggest relationship with the C-IMT among
the 4 obesity indices. However, there were no statistical
significant differences and no best predictor was found. For
the women, the obesity incidences and C-IMT showed no
relationships.
Conclusions : This study suggested that obesity in
adolescence was related to an increase C-IMT in healthy
young Korean men.

영어초록

Objectives : The aim of this study is to investigate the
association between obesity indices (body mass index,
weight, waist-hip ratio and waist circumference) in
adolescents and the carotid intima-media thickness (C-IMT)
in early adulthood. We also wanted to identify the best
predictor for C-IMT among these obesity indices.
Methods : This study used community-based prospective
cohort study, known as the Kangwha Study, and the data
we used were from subjects who were 16-years old in 1996
(defined as HadolescenceI) and 25 years-old in 2005
(defined as Hearly adulthoodI). The 256 subjects (113 men
and 143 women) who were used for analysis participated in
both follow-ups, and they underwent B-mode
ultrasonography of the carotid arteries at the early
adulthood follow-up. Obesity indices were defined as the
body mass index, weight, waist-hip ratio and waist
circumference. The C-IMT was defined as the mean of the
maximal IMT of each common carotid artery. The C-IMT
and obesity indices associations were evaluated via
multivariable regression, logistic regression and the
receiver-operator characteristic curve analyses.
Results : In men, all the obesity indices in adolescence
were showed to have statistically significant positive
association with C-IMT in early adulthood. However, no
such relationship was showed in women. On multiple
regression and logistic regression analysis, the waist-hip
ratio showed the biggest relationship with the C-IMT among
the 4 obesity indices. However, there were no statistical
significant differences and no best predictor was found. For
the women, the obesity incidences and C-IMT showed no
relationships.
Conclusions : This study suggested that obesity in
adolescence was related to an increase C-IMT in healthy
young Korean men.

참고자료

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