내시경적 경접형동 접근법 후 발생하는 비부비동 합병증: 단일기관 연구 (Sinonasal Complications after Endoscopic Transsphenoidal Approach: A Single Center Study)

서지정보

· 발행기관 : 대한이비인후과학회 부산,울산,경남 지부회
· 수록지 정보 : 임상이비인후과 / 33권 / 4호 / 193 ~ 202페이지
· 저자명 : 장효범, 이재민, 박다희, 노환중, 이치형, 성순기, 조규섭, 문수진

초록

Background and Objectives: The endoscopic transsphenoidal approach (TSA) is the standardized surgical approach to sella lesions providing a wider field and resulting in fewer neurosurgical complications. However, sinonasal complications are relatively less studied. This study aims to analyze sinonasal morbidities after endoscopic TSA performed by a single center. Materials and Methods: Among 154 patients who underwent endoscopic TSA from 2015 to 2022, 107 patients who were followed up for more than 3 months were included and retrospectively reviewed. Sinonasal complications including crust, discharge, septal perforation, synechia and polypoid sphenoid mucosa at postoperative 3 month were evaluated with olfactory function. The patients were subdivided into nasoseptal flap (NSF), non-NSF, 1st phase (initial 3 years, n=53) and 2nd phase (later 4 years, n=54) groups for further analysis. Results: There were 47 male (43.9%) with a mean age of 51.6 (range 15–83). The mean follow-up duration was 10.9 (range 3–46) months. Crust (28, 26.2%) was the most frequent morbidity followed by synechia (18, 16.8%), hyposmia (17, 15.9%), discharge (14, 13.1%), polypoid sphenoid mucosa and septal perforation (8, 7.5%). NSF was associated with crust formation and septal perforation (p<0.001). Olfactory function was relatively preserved at 3 month (p=0.065). Post- operative cerebrospinal fluid (CSF) leak decreased in the 2nd phase (4/54, 7.4%) compared to the 1st phase (12/53, 22.6%) (p<0.05). Conclusion: Crust was the most frequent sinonasal morbidity after endoscopic TSA followed by synechia. NSF was associated with crust and septal perforation. Post-op CSF leaks could be reduced after overcoming the learning curve of endoscopic TSA.

영어초록

Background and Objectives: The endoscopic transsphenoidal approach (TSA) is the standardized surgical approach to sella lesions providing a wider field and resulting in fewer neurosurgical complications. However, sinonasal complications are relatively less studied. This study aims to analyze sinonasal morbidities after endoscopic TSA performed by a single center. Materials and Methods: Among 154 patients who underwent endoscopic TSA from 2015 to 2022, 107 patients who were followed up for more than 3 months were included and retrospectively reviewed. Sinonasal complications including crust, discharge, septal perforation, synechia and polypoid sphenoid mucosa at postoperative 3 month were evaluated with olfactory function. The patients were subdivided into nasoseptal flap (NSF), non-NSF, 1st phase (initial 3 years, n=53) and 2nd phase (later 4 years, n=54) groups for further analysis. Results: There were 47 male (43.9%) with a mean age of 51.6 (range 15–83). The mean follow-up duration was 10.9 (range 3–46) months. Crust (28, 26.2%) was the most frequent morbidity followed by synechia (18, 16.8%), hyposmia (17, 15.9%), discharge (14, 13.1%), polypoid sphenoid mucosa and septal perforation (8, 7.5%). NSF was associated with crust formation and septal perforation (p<0.001). Olfactory function was relatively preserved at 3 month (p=0.065). Post- operative cerebrospinal fluid (CSF) leak decreased in the 2nd phase (4/54, 7.4%) compared to the 1st phase (12/53, 22.6%) (p<0.05). Conclusion: Crust was the most frequent sinonasal morbidity after endoscopic TSA followed by synechia. NSF was associated with crust and septal perforation. Post-op CSF leaks could be reduced after overcoming the learning curve of endoscopic TSA.

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