비글견에서 발생한 전반적 대뇌허혈 (Global Cerebral Ischemia in a Beagle Dog)

서지정보

· 발행기관 : 한국임상수의학회
· 수록지 정보 : 한국임상수의학회지 / 26권 / 1호 / 104 ~ 108페이지
· 저자명 : 최호정, 최수영, 안지영, 오이세, 정성목, 조성환, 이영원

초록

Global cerebral ischemia occurs commonly in patients who have a variety of clinical conditions including
cardiac arrest and shock. Cerebral ischemia results in a rapid depletion of energy stores that triggers resulting in
excitotoxic death. Imaging studies of the brain with computed tomography(CT) or magnetic resonance imaging(MRI)
are necessary to confirm the clinical neurolocalization, identify any associated mass effect, and rule out other causes
of focal brain disorders. Cardiopulmonary arrest was occurred by propofol anesthesia in a 1 year old, intact female
Beagle dog. After successful cardiopulmonary resuscitation was performed within 5 minutes, clinical signs such as
vocalization, paddling, opisthotonus and seizure were represented. At the 12th day, CT and MRI examinations of the
brain were performed to evaluate the brain. After euthanasia, histopathologic examination was performed. On transverse
image of CT, lesions appeared as a hypodense in the right dorsal surface of the frontal lobe and level of optic canal,
and dorsomedial surface of occipital lobe of cerebrum. No contrast enhancement was represented following intravenous
contrast administration. On MR images of brain, the lesions were seen as a hyperintense on T2-weighted(T2W) images
and a isointense or mild hypointense on T1-weighted(T1W) images. Hyperintense lesions both T2W and T1W images
were observed at the surrounding cerebral sulcus. There was no significant signal changes on contrast T1WI.
Histopathologic examination after euthanasia revealed that the lesion was necrosis of the cerebral cortex caused by
cerebral ischemia.

영어초록

Global cerebral ischemia occurs commonly in patients who have a variety of clinical conditions including
cardiac arrest and shock. Cerebral ischemia results in a rapid depletion of energy stores that triggers resulting in
excitotoxic death. Imaging studies of the brain with computed tomography(CT) or magnetic resonance imaging(MRI)
are necessary to confirm the clinical neurolocalization, identify any associated mass effect, and rule out other causes
of focal brain disorders. Cardiopulmonary arrest was occurred by propofol anesthesia in a 1 year old, intact female
Beagle dog. After successful cardiopulmonary resuscitation was performed within 5 minutes, clinical signs such as
vocalization, paddling, opisthotonus and seizure were represented. At the 12th day, CT and MRI examinations of the
brain were performed to evaluate the brain. After euthanasia, histopathologic examination was performed. On transverse
image of CT, lesions appeared as a hypodense in the right dorsal surface of the frontal lobe and level of optic canal,
and dorsomedial surface of occipital lobe of cerebrum. No contrast enhancement was represented following intravenous
contrast administration. On MR images of brain, the lesions were seen as a hyperintense on T2-weighted(T2W) images
and a isointense or mild hypointense on T1-weighted(T1W) images. Hyperintense lesions both T2W and T1W images
were observed at the surrounding cerebral sulcus. There was no significant signal changes on contrast T1WI.
Histopathologic examination after euthanasia revealed that the lesion was necrosis of the cerebral cortex caused by
cerebral ischemia.

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