운동에서 ROS의 양날의 검 역할에 대한 연구 (ROS as a double-edged sword in exercise)

서지정보

· 발행기관 : 한국체육과학회
· 수록지 정보 : 한국체육과학회지 / 32권 / 4호 / 581 ~ 593페이지
· 저자명 : 사영초, 곡유, 이진우, 김재철

초록

Purpose: Previous studies have suggested that ROS can bring negative effects to the body, such as sports injuries and inflammatory responses. With the deepening of research in recent years, it has been found that ROS also play other roles in the body, such as promoting autophagy and lowering blood sugar. Currently, there is no consensus in academic circles on the conditions under which ROS can have positive and negative effects. The role of ROS in the organism is still under research. Therefore, this paper summarises the positive and negative effects of ROS in the light of the latest research. Through a comprehensive discussion of the role of ROS, it provides a theoretical basis for the promotion of health through exercise, and aims to avoid the side effects caused by ROS production during exercise through human intervention.
Conclusion: The positive effects of ROS mainly include: (1) Promote the transcription of antioxidant enzymes. (2) Trigger physiological programmed cell death to prevent cancer. (3) Promote mitochondrial biogenesis. (4) Promote the proliferation and differentiation of stem cells (5) Increase the uptake of blood sugar by cells. (6) Promote muscle hypertrophy. The negative effects of ROS are: (1) The oxidized phospholipid bilayer destroys the integrity of the cell membrane. (2) A chain reaction that causes fatty acid oxidation. (3) Cause an inflammatory response. (4) Destruction of protein structure. (5) Cause DNA damage. (6) Reduced exercise capacity. ROS is a double-edged sword. During exercise, the damage caused by ROS to the organism can be reduced and its positive effects can be maximised by controlling the intensity and duration of exercise and supplementing antioxidants at the right time. Therefore, how to use ROS scientifically may become the focus of future research.

영어초록

Purpose: Previous studies have suggested that ROS can bring negative effects to the body, such as sports injuries and inflammatory responses. With the deepening of research in recent years, it has been found that ROS also play other roles in the body, such as promoting autophagy and lowering blood sugar. Currently, there is no consensus in academic circles on the conditions under which ROS can have positive and negative effects. The role of ROS in the organism is still under research. Therefore, this paper summarises the positive and negative effects of ROS in the light of the latest research. Through a comprehensive discussion of the role of ROS, it provides a theoretical basis for the promotion of health through exercise, and aims to avoid the side effects caused by ROS production during exercise through human intervention.
Conclusion: The positive effects of ROS mainly include: (1) Promote the transcription of antioxidant enzymes. (2) Trigger physiological programmed cell death to prevent cancer. (3) Promote mitochondrial biogenesis. (4) Promote the proliferation and differentiation of stem cells (5) Increase the uptake of blood sugar by cells. (6) Promote muscle hypertrophy. The negative effects of ROS are: (1) The oxidized phospholipid bilayer destroys the integrity of the cell membrane. (2) A chain reaction that causes fatty acid oxidation. (3) Cause an inflammatory response. (4) Destruction of protein structure. (5) Cause DNA damage. (6) Reduced exercise capacity. ROS is a double-edged sword. During exercise, the damage caused by ROS to the organism can be reduced and its positive effects can be maximised by controlling the intensity and duration of exercise and supplementing antioxidants at the right time. Therefore, how to use ROS scientifically may become the focus of future research.

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